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A New Biocompatible Release Material Based on Branched Polyvinyl Alcohol

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Abstract

The antiadhesive properties and biocompatibility of porous and nonporous films based on branched polyvinyl alcohol were evaluated. A nonporous film of branched polyvinyl alcohol has been shown to preserve the intestinal epithelium and cause only slight inflammation and edema. On the contrary, implantation of a porous film induced fibrin formation and severe inflammation and ensured only focal preservation of the intestinal epithelium.

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Funding

The work was carried out with the financial support of the Ministry of Science and Higher Education of the Russian Federation within the framework of a state order, project no. FSSM-2020-0004.

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Authors and Affiliations

  1. Mendeleev University of Chemical Technology of Russia, 125047, Moscow, Russia

    S. V. Osadchenko, M. V. Sten’kina, Ya. O. Mezhuev & M. I. Shtil’man

Authors
  1. S. V. Osadchenko
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  2. M. V. Sten’kina
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  3. Ya. O. Mezhuev
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  4. M. I. Shtil’man
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Corresponding author

Correspondence to S. V. Osadchenko.

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Translated by M. Drozdova

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Osadchenko, S.V., Sten’kina, M.V., Mezhuev, Y.O. et al. A New Biocompatible Release Material Based on Branched Polyvinyl Alcohol. Polym. Sci. Ser. D 15, 436–440 (2022). https://doi.org/10.1134/S1995421222030200

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  • DOI: https://doi.org/10.1134/S1995421222030200

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