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Synthesis of N,N′-Bis(arylsulfanyl)cyclohexa-2,5-diene-1,4-diimines and N,N′-(Cyclohexa-2,5-diene-1,4-diylidene)bis(arenesulfinamides)

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Abstract

Reactions of (chlorosulfanyl)benzenes with benzene-1,4-diamines afforded new N,N′-bis(arylsul­fanyl)cyclohexa-2,5-diene-1,4-diimines which were oxidized to N,N′-(cyclohexa-2,5-diene-1,4-diylidene)­bis(arenesulfinamides) with 2 equiv of m-chloroperoxybenzoic acid. When the oxidation was carried out using 4 equiv of m-chloroperoxybenzoic acid, the corresponding bis-sulfonamides were obtained. The synthesized compounds were predicted in silico to exhibit biological activity with a high probability.

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Authors and Affiliations

  1. Donbass State Engineering Academy, 84313, Kramatorsk, Ukraine

    S. A. Konovalova, A. P. Avdeenko & A. A. Santalova

Authors
  1. S. A. Konovalova
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  2. A. P. Avdeenko
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  3. A. A. Santalova
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Correspondence to A. P. Avdeenko.

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Translated from Zhurnal Organicheskoi Khimii, 2021, Vol. 57, No. 4, pp. 532–540 https://doi.org/10.31857/S051474922104008X.

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Konovalova, S.A., Avdeenko, A.P. & Santalova, A.A. Synthesis of N,N′-Bis(arylsulfanyl)cyclohexa-2,5-diene-1,4-diimines and N,N′-(Cyclohexa-2,5-diene-1,4-diylidene)bis(arenesulfinamides). Russ J Org Chem 57, 551–557 (2021). https://doi.org/10.1134/S1070428021040084

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