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Synthesis and Characterization of Some New Indoline-Based 1,2,4-Triazole Derivatives

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Abstract

Three-component reaction of substituted benzoyl chlorides, ammonium thiocyanate, and isatin in anhydrous acetone gave a series of novel N-(2,3-dioxo-2,3-dihydro-1H-indole-1-carbothioyl)benzamides, and condensation of the latter with hydrazine hydrate in anhydrous ethanol under reflux afforded 1-(5-(aryl)-4H-1,2,4-triazol-3-yl)-2,3-dihydro-1H-indole-2,3-dione derivatives. The structure of the synthesized compounds was confirmed by elemental analyses and FT-IR and 1H and 13C NMR data.

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Authors and Affiliations

  1. Chemistry Department, Tonekabon Branch, Islamic Azad University, 46841-61167, Tonekabon, Iran

    N. Afshar, F. Hatamjafari, K. Pourshamsian & A. R. Oliaey

  2. Young Researchers and Elite Club, East Tehran Branch, Islamic Azad University, 18661-13118, Tehran, Iran

    A. Shiroudi

Authors
  1. N. Afshar
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  2. F. Hatamjafari
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  3. A. Shiroudi
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  4. K. Pourshamsian
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  5. A. R. Oliaey
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Correspondence to F. Hatamjafari or A. Shiroudi.

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Afshar, N., Hatamjafari, F., Shiroudi, A. et al. Synthesis and Characterization of Some New Indoline-Based 1,2,4-Triazole Derivatives. Russ J Org Chem 56, 2153–2158 (2020). https://doi.org/10.1134/S1070428020120179

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  • DOI: https://doi.org/10.1134/S1070428020120179

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