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9α-hydroxylation of 25-fluoroponasterone a diacetonide in lithium-ammonia solution

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Abstract

25-Fluoroponasterone A diacetonide reacted with lithium in liquid ammonia to give 25-fluoro-9α,20-dihydroxyecdysone diacetonide whose hydrolysis afforded 25-fluoro-9α,20-dihydroxyecdysone 20,22-acetonide. Nonfluorinated analog of the latter was isolated previously from Silene italica ssp. nemoralis.

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Authors and Affiliations

  1. Institute of Petrochemistry and Catalysis, Russian Academy of Sciences, pr. Oktyabrya 141, Ufa, 450075, Bashkortostan, Russia

    S. R. Afon’kina, R. G. Savchenko, N. A. Ves’kina, I. V. Galyautdinov & V. N. Odinokov

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  1. S. R. Afon’kina
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  2. R. G. Savchenko
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  3. N. A. Ves’kina
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  4. I. V. Galyautdinov
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  5. V. N. Odinokov
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Correspondence to V. N. Odinokov.

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Original Russian Text © S.R. Afon’kina, R.G. Savchenko, N.A. Ves’kina, I.V. Galyautdinov, V.N. Odinokov, 2012, published in Zhurnal Organicheskoi Khimii, 2012, Vol. 48, No. 3, pp. 462–464.

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Afon’kina, S.R., Savchenko, R.G., Ves’kina, N.A. et al. 9α-hydroxylation of 25-fluoroponasterone a diacetonide in lithium-ammonia solution. Russ J Org Chem 48, 463–466 (2012). https://doi.org/10.1134/S1070428012030232

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  • DOI: https://doi.org/10.1134/S1070428012030232

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