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Domino Multicomponent Intramolecular Cyclization Strategy for the Multi Functionalized Imidazo[1,2-a]pyrimidin-5(1H)-one Derivatives

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Abstract

A microwave assisted novel domino synthetic approach to trifluoromethyl substituted imidazo[1,2-a]pyrimidin-5(1H)-one derivatives has been developed via a multi component cascade strategy in a single operation. The synthesized compounds can find application as structural components of biologically active compounds.

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Authors and Affiliations

  1. K.L. Education Foundation (Deemed to be University), Vaddeswaram, 522502, Guntur, India

    P. R. Khan & K. Deepti

  2. Department of Pharmacy, SANA College of Pharmacy, Telangana, 508206, Kodad, India

    P. R. Khan & G. R. Alugubelli

  3. Department of Chemistry, Acharya Nagarjuna University, Nagarjuna Nagar, 522510, Andhra Pradesh, India

    R. Sireesha

  4. Department of Biomedical Sciences and Therapeutics, Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Kota Kinabalu, 88400, Sabah, Malaysia

    P. V. Rao

  5. Department of Chemistry, Krishna University, Krishna Distrist, 521003, Andhra Pradesh, India

    M. V. B. Rao

Authors
  1. P. R. Khan
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  2. G. R. Alugubelli
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  3. R. Sireesha
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  4. K. Deepti
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  5. P. V. Rao
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  6. M. V. B. Rao
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Corresponding author

Correspondence to M. V. B. Rao.

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Khan, P.R., Alugubelli, G.R., Sireesha, R. et al. Domino Multicomponent Intramolecular Cyclization Strategy for the Multi Functionalized Imidazo[1,2-a]pyrimidin-5(1H)-one Derivatives. Russ J Gen Chem 91, 1123–1127 (2021). https://doi.org/10.1134/S1070363221060219

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  • DOI: https://doi.org/10.1134/S1070363221060219

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