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1-(3,3-Diethoxypropyl)-1-[(dihexylphosphoryl)methyl]-3-phenylurea in the Synthesis of 4-Aryl-Substituted Tetrahydropyrimidin-2-ones

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Abstract

First specimens of 4-aryl-substituted tetrahydropyrimidin-2(1H)-ones containing a phosphoryl group were obtained through the reaction of 1-(3,3-diethoxypropyl)-1-[(dihexylphosphoryl)methyl]-3-phenylurea with resorcinol and its derivatives in the presence of trifluoroacetic acid.

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References

  1. Kappe, C.O., Acc. Chem. Res., 2000, vol. 33, p. 879. doi 10.1021/ar000048h

    Article  CAS  PubMed  Google Scholar 

  2. Jetti, S.R., Upadhyaya, A., and Jain, S., Med. Chem. Res., 2014, vol 23, p. 4356. doi 10.1007/s00044-014-0988-y

    Article  CAS  Google Scholar 

  3. Amir, M., Javed, S.A., and Kumar, H., Acta Pharm., 2008, vol. 58, p. 467. doi 10.2478/v10007-008-0028-x

    Article  CAS  PubMed  Google Scholar 

  4. Soumyanarayanan, U., Bhat, V.G., Kar, S.S., and Mathew, J.A., Org. Med. Chem. Lett., 2012, vol. 2, no. 23, p. 1. doi 10.1186/2191-2858-2-23

    Google Scholar 

  5. Gong, D., Zhang, L., and Yuan, C., Heteroatom Chem., 2003, vol. 14, no. 1, p. 13. doi 10.1002/hc.10058

    Article  CAS  Google Scholar 

  6. Zigeuner, G. and zur Hausen, M., Monatsh. Chem., 1961, vol. 92, p. 278. doi 10.1007/BF01153882

    Article  CAS  Google Scholar 

  7. Vagapova, L.I., Voronina, J.K., Sykaev, V.V., Burilov, A.R., Garifzyanov, A.R., and Pudovik, M.A., Mendeleev Commun., 2018, vol. 28, no. 4, p. 398. doi 10.1016/j.mencom.2018.07.019

    Article  CAS  Google Scholar 

  8. Vagapova, L.I., Amirova, L.R., Burilov, A.R., Garifzyanov, A.R., Pudovik, M.A., and Kharlampidi, Kh.E., Russ. J. Org. Chem., 2014, vol. 50, no. 6, p. 778. doi 10.1134/S1070428014060025

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. A.E. Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, ul. Akademika Arbuzova 8, Kazan, Tatarstan, 420088, Russia

    L. I. Vagapova, A. R. Burilov & M. A. Pudovik

  2. Kazan National Research Technological University, Kazan, Tatarstan, Russia

    K. V. Matylitskii

  3. Kazan (Volga Region) Federal University, Kazan, Tatarstan, Russia

    A. R. Garifzyanov

Authors
  1. L. I. Vagapova
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  2. K. V. Matylitskii
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  3. A. R. Burilov
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  4. A. R. Garifzyanov
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  5. M. A. Pudovik
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Corresponding author

Correspondence to L. I. Vagapova.

Additional information

Dedicated to the 115th anniversary of B.A. Arbuzov’s birth

Original Russian Text © L.I. Vagapova, K.V. Matylitskii, A.R. Burilov, A.R. Garifzyanov, M.A. Pudovik, 2018, published in Zhurnal Obshchei Khimii, 2018, Vol. 88, No. 11, pp. 1920–1922.

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Vagapova, L.I., Matylitskii, K.V., Burilov, A.R. et al. 1-(3,3-Diethoxypropyl)-1-[(dihexylphosphoryl)methyl]-3-phenylurea in the Synthesis of 4-Aryl-Substituted Tetrahydropyrimidin-2-ones. Russ J Gen Chem 88, 2442–2444 (2018). https://doi.org/10.1134/S1070363218110312

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  • DOI: https://doi.org/10.1134/S1070363218110312

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