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An Efficient Synthesis of (R or S)-4-Methyl-1-(1,4,5,8-tetramethoxynaphthalen-2-yl)pent-3-ene-1-thiol

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Abstract

Based on thilation by the Lawesson’s reagent (LR), a concise and efficient synthesis of (R or S)-4-methyl-1-(1,4,5,8-tetramethoxynaphthalen-2-yl)pent-3-ene-1-thiol was developed with relatively high yield.

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Authors and Affiliations

  1. School of Pharmacy, Shanghai Jiao Tong University, Shanghai, 200240, China

    Guang Huang, Wen Zhou, Qing-qing Meng, Qi-jing Zhang, Jin-yun Dong & Shao-shun Li

  2. Shanghai Institute of Pharmaceutical Industry, Shanghai, 201203, China

    Guang Huang & Bao-quan Zhu

  3. School of Pharmaceutical Sciences and Chemistry, Dali University, Dali, 671000, China

    Hui-ran Zhao

Authors
  1. Guang Huang
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  2. Hui-ran Zhao
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  3. Wen Zhou
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  4. Qing-qing Meng
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  5. Qi-jing Zhang
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  6. Jin-yun Dong
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  7. Bao-quan Zhu
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  8. Shao-shun Li
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Corresponding authors

Correspondence to Qing-qing Meng or Shao-shun Li.

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The text was submitted by the authors in English.

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Huang, G., Zhao, Hr., Zhou, W. et al. An Efficient Synthesis of (R or S)-4-Methyl-1-(1,4,5,8-tetramethoxynaphthalen-2-yl)pent-3-ene-1-thiol. Russ J Gen Chem 87, 2995–2999 (2017). https://doi.org/10.1134/S1070363217120441

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  • DOI: https://doi.org/10.1134/S1070363217120441

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