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Synthesis and reactions of novel pyridine-bridged-2,6-bis-carboxamide hydrazones

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Abstract

A number of new hydrazones bearing pyridine-2,6-bis-carboxamides were synthesized and elucidated by spectral and elemental analysis. 2,6-Bis-carboxamide pyridine hydrazide was treated with various active carbonyl compounds containing formyl or methanoyl groups to give hydrazones and Schiff bases.

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References

  1. Sheela, J., Navita, K., Deepak, K., and Rakesh, S., Bioorg. Med. Chem. Lett., 2005, vol. 15(1), p. 221. DOI: 10.1016/jbmcl.2004.09.084.

    Article  Google Scholar 

  2. Reddy, M.V., Su, C.R., Chiou, W.F., Liu, Y.N., Chen, R.Y., Bastow, K.F., Lee, K.H., and Wu, T.S., Bioorg. Med. Chem., 2008,vol. 6(15), p. 7358. DOI: 10.1016/jbmc.2008.06.018.

    Article  Google Scholar 

  3. Sheela, J., Navita, K., and Prapti, T., Bioorg. Med. Chem., 2004, vol. 12(3), p. 571. DOI: 10.1016/jbmc.2003.11.001.

    Article  Google Scholar 

  4. Mohammed, E. and Abd El-Galil, A., Russ. J Gen. Chem., 2015, vol. 85, no. 5, p. 1513. DOI: 10.1134/S1070363215050262.

    Google Scholar 

  5. El-Tombary, A.A., Sci. Pharm., 2013, vol. 81(2), p. 393. DOI: 10.3797/scipharm.1211-21.

    Article  CAS  Google Scholar 

  6. Akbar, M. and Mahsa, J., Res. Chem. Intermed., 2015, vol. 41, p. 511. DOI: 10.1007/s11164-013-1205-1.

    Article  Google Scholar 

  7. Kamel, M.M., Ali, H.I., Anwar, M.M., Mohamed, N.A., and Soliman, A.M., Eur. J. Med. Chem., 2010, vol. 45(2), p. 572. DOI: 10.1016/jejmech.2009.10.044.

    Article  CAS  Google Scholar 

  8. Siddiqui, N., Pandeya, SN., Khan, SA., James, S., Rana, A., and Mahfuz, A., Bioorg. Med. Chem. Lett., 2007, vol. 17, p. 255.

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Pharmaceutical Chemistry Department, Drug Exploration & Development Chair (DEDC), College of Pharmacy, King Saud University, Riyadh, 11451, Saudi Arabia

    N. M. Khalifa & A. E. Amr

  2. Department of Therapeutical Chemistry, Pharmaceutical and Drug Industries Division, National Research Centre, Dokki, Cairo, 12622, Egypt

    N. M. Khalifa

  3. Chemistry Department, Girls College of Science, King Khalid University, Abha, 9004, Saudi Arabia

    N. M. Sabry

  4. Applied Organic Chemistry Department, National Research Centre, Dokki, Cairo, 12622, Egypt

    N. M. Sabry & A. E. Amr

Authors
  1. N. M. Khalifa
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  2. N. M. Sabry
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  3. A. E. Amr
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Correspondence to N. M. Khalifa.

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The text was submitted by the authors in English.

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Khalifa, N.M., Sabry, N.M. & Amr, A.E. Synthesis and reactions of novel pyridine-bridged-2,6-bis-carboxamide hydrazones. Russ J Gen Chem 86, 1434–1437 (2016). https://doi.org/10.1134/S1070363216060323

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  • DOI: https://doi.org/10.1134/S1070363216060323

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