Abstract
Treatment of 5-hydrazino-2-phenyl-1,3-oxazole-4-carbonitrile with acetylacetone lead to the formation of a substituted pyrazole residue on C5, which enhanced the electrophilicity of the cyano group in position 4 so that it became capable of reacting with hydrogen sulfide, sodium azide, and hydroxylamine. As a result, the corresponding azole fragments were introduced into position 4 of the 5-(1H-pyrazol-1-yl)-1,3-oxazole system.
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Original Russian Text © O.V. Shablykin, V.S. Brovarets, B.S. Drach, 2007, published in Zhurnal Obshchei Khimii, 2007, Vol. 77, No. 5, pp. 842–845.
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Shablykin, O.V., Brovarets, V.S. & Drach, B.S. New transformations of 5-Hydrazino-2-phenyl-1,3-oxazole-4-carbonitrile. Russ J Gen Chem 77, 936–939 (2007). https://doi.org/10.1134/S1070363207050210
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DOI: https://doi.org/10.1134/S1070363207050210