Skip to main content
SpringerLink
Log in

Optimization of photothermal methods for laser hyperthermia of malignant cells using bioconjugates of gold nanoparticles

  • Published:
Colloid Journal Aims and scope Submit manuscript

Abstract

Selective action of laser radiation on membranes of malignant cells has been studied in different regimes using conjugates of gold nanoparticles with oligonucleotides by the example of DNA aptamers. Under the conditions of a contact between a bioconjugate and a cell surface and the development of substantial and rapidly relaxing temperature gradients near a nanoparticle, the membranes of malignant cells alone are efficiently damaged due to the local hyperthermia of a cellular membrane. It has been shown that employment of pulsed instead of continuous wave laser radiation provides the localization of the damaging action, which does not involve healthy cells.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Khlebtsov, N.G., Kvant. Elektron., 2008, vol. 38, p. 504.

    Article  CAS  Google Scholar 

  2. Chumakov, D.S., Basko, M.V., Dikht, N.I., Bucharskaya, A.B., Rodionova, T.I., and Terentyuk, G.S., Saratovsk. Nauchno-Med. Zh., 2013, vol. 9, p. 700.

    CAS  Google Scholar 

  3. Habash, R.W.Y., Bansal, R., Krewski, D., and Alhafid, H.T., Crit. Rev. Biomed. Eng., 2007, vol. 35, p. 37.

    Article  Google Scholar 

  4. Huang, X., Jain, P.K., El-Sayed, I.H., and ElSayed, M.A., Laser Med. Sci., 2008, vol. 23, p. 217.

    Article  Google Scholar 

  5. Lapotko, D., Nanomedicine, 2009, vol. 4, p. 253.

    Article  Google Scholar 

  6. Lukianova-Hleb, E., Hu, Y., Latterini, L., Tarpani, L., Lee, S., Drezek, R.A., Hafner, J.H., and Lapotko, D.O., ACS Nano, 2010, vol. 4, p. 2109.

    Article  CAS  Google Scholar 

  7. Tuchin, V., Opticheskaya biomeditsinskaya diagnostika (Optical Biomedical Diagnostics), Moscow Fizmatlit, 2007.

    Google Scholar 

  8. Huang, X. and El-Sayed, M.A., J. Adv. Res., 2010, vol. 1, p. 13.

    Article  Google Scholar 

  9. Elbialy, N., Abdelhamid, M., and Youssef, T., J. Biomed. Nanotechnol., 2010, vol. 6, p. 687.

    Article  CAS  Google Scholar 

  10. Dreaden, E.C., Mackey, M.A., Huang, X., Kang, B., and El-Sayed, M.A., Chem. Soc. Rev., 2011, vol. 40, p. 3391.

    Article  CAS  Google Scholar 

  11. Dykman, L. and Khlebtsov, N., Chem. Soc. Rev., 2012, vol. 41, p. 2256.

    Article  CAS  Google Scholar 

  12. Zhang, J., Liu, B., Liu, H., Zhang, X., and Tan, W., Nanomedicine, 2013, vol. 8, p. 983.

    Article  CAS  Google Scholar 

  13. Reinemann, C. and Strehlitz, B., Swiss Medical Weekly, 2014, vol. 144, p. 13908.

    Google Scholar 

  14. Zamay, G.S., Kolovskaya, O.S., Zamay, T.N., Glazyrin, Y.E., Krat, A.V., Zubkova, O., Spivak, E., Wehbe, M., Gargaun, A., Muharemagic, D., Komarova, M., Grigorieva, V., Savchenko, A., Modestov, A.A., Berezovski, M.V., and Zamay, A.S., Mol. Ther., 2015, vol. 23, p. 1486.

    Article  CAS  Google Scholar 

  15. Huang, X., El-Sayed, I.H., Qian, W., and ElSayed, M.A., J. Am. Chem. Soc., 2006, vol. 128, p. 2115.

    Article  CAS  Google Scholar 

  16. Von Maltzahn, G., Park, J.-H., Agrawal, A., Bandaru, N.K., Das, S.K., Sailor, M.J., and Bhatia, S.N., Cancer Res., 2009, vol. 69, p. 3892.

    Article  Google Scholar 

  17. Afifi, M.M., El Sheikh, S.M., Abdelsalam, M.M., Ramadan, H., Omar, T.A., El Tantawi, M., AbdelRazek, K.M., and Mohamed, M., Oral. Surg., Oral. Med., Oral. Pathol., Oral. Radiol., 2013, vol. 115, p. 743.

    Article  Google Scholar 

  18. Lukianova-Hleb, E.Y., Hanna, E.Y., Hafner, J.H., and Lapotko, D.O., Nanotechnology, 2010, vol. 21, p. 085102.

    Article  CAS  Google Scholar 

  19. Hirsch, L.R., Stafford, R.J., Bankson, J.A., Sershen, S.R., Rivera, B., Price, R.E., Hazle, J.D., Halas, N.J., and West, J.L., Proc. Natl. Acad. Sci. USA, 2003, vol. 100, p. 13549.

    Article  CAS  Google Scholar 

  20. Loo, C., Lin, A., Hirsch, L., Lee, M.H., Barton, J., Halas, N., West, J., and Drezek, R., Technol. Cancer Res. Treat., 2004, vol. 3, p. 33.

    Article  CAS  Google Scholar 

  21. Maksimova, I.L., Akchurin, G.G., Khlebtsov, B.N., Terentyuk, G.S., Akchurin, G.G., Ermolaev, I.A., Skaptsov, A.A., Soboleva, E.P., Khlebtsov, N.G., and Tuchin, V.V., Med. Laser Appl., 2007, vol. 22, p. 199.

    Article  Google Scholar 

  22. Greisch, K., J. Drug. Target., 2007, vol. 15, p. 457.

    Article  Google Scholar 

  23. Hleb, E.Y., Hafner, J.H., Myers, J.N., Hanna, E.Y., Rostro, B.C., Zhdanok, S.A., and Lapotko, D.O., Nanomedicine, 2008, vol. 3, p. 647.

    Article  CAS  Google Scholar 

  24. Gavrilyuk, A.P. and Karpov, S.V., Appl. Phys. B, 2009, vol. 97, p. 163.

    Article  CAS  Google Scholar 

  25. Ershov, A.E., Gavrilyuk, A.P., Karpov, S.V., and Semina, P.N., Appl. Phys. B, 2014, vol. 115, p. 547.

    Article  CAS  Google Scholar 

  26. Pitsillides, C.M., Joe, E.K., Wei, X., Anderson, R.R., and Lin, C.P., Biophys. J., 2003, vol. 84, p. 4023.

    Article  CAS  Google Scholar 

  27. Kozlov, M.M. and Chernomordik, L.V., Curr. Opin. Struct. Biol., 2015, vol. 33, p. 61.

    Article  CAS  Google Scholar 

  28. Markel, V.A., Muratov, L.S., Stockman, M.I., and George, T.F., Phys. Rev. B: Condens. Matter, 1991, vol. 43, p. 8183.

    Article  Google Scholar 

  29. Johnson, P.B. and Christy, R.W., Phys. Rev. B: Condens. Matter, 1972, vol. 6, p. 4370.

    Article  CAS  Google Scholar 

  30. Markel, V.A., Shalaev, V.M., Stechel, E.B., Kim, W., and Armstrong, R.L., Phys. Rev. B: Condens. Matter, 1996, vol. 53, p. 2425.

    Article  CAS  Google Scholar 

  31. Hasgall, P.A., Gennaro, D.F., Baumgartner, C., Neufeld, E., Gosselin, M.C., Payne, D., Klingenbock, A., and Kuster, N., ITIS Database for Thermal and Electromagnetic Parameters of Biological Tissues, 2015, Version 3.0. doi: 10.13099/VIP21000-03-0.

    Google Scholar 

  32. Lee, R.C., Aarsvold, J.N., Chen, W., Astumian, R.D., Kelley, K.M., and Pliskin, N.H., Semin. Neurol., 1995, vol. 15, p. 367.

    Article  CAS  Google Scholar 

  33. Cravalho, E.G., Toner, M., Taylor, D.C., and Lee, R.C., in Electrical Trauma: The Pathophysiology, Manifestations and Clinical Management, Lee, R.C., Cravalho, E.G., and Burke, J.F., Eds., Cambridge: Cambridge Univ. Press, 1992, p. 281.

  34. Genfol’d, M.L. and Barchuk, A.S., Lazernaya selektivnaya gipertermiya v lechenii zlokachestvennykh novoobrazovanii. Metodicheskie rekomendatsii (Laser Selective Hyperthermia in Therapy of Malignant Tumors. Methodical Recommemdations), St. Petersburg GUN NII onkologii im. N.N. Petrova, 2002.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Siberian Federal University, Svobodnyi pr. 79, Krasnoyarsk, 660041, Russia

    V. S. Gerasimov, A. E. Ershov, S. V. Karpov & S. P. Polyutov

  2. Institute of Computational Modeling, Siberian Branch, Russian Academy of Sciences, Akademgorodok 50/44, Krasnoyarsk, 660036, Russia

    A. E. Ershov

  3. Kirenskii Institute of Physics, Siberian Branch, Russian Academy of Sciences, Akademgorodok 50/38, Krasnoyarsk, 660036, Russia

    A. E. Ershov, S. V. Karpov & P. N. Semina

  4. Reshetnev State Siberian State Aerospace University, pr. Gazety “Krasnoyarskii rabochii” 31, Krasnoyarsk, 660037, Russia

    S. V. Karpov

Authors
  1. V. S. Gerasimov
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. A. E. Ershov
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. S. V. Karpov
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. S. P. Polyutov
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. P. N. Semina
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to S. V. Karpov.

Additional information

Original Russian Text © V.S. Gerasimov, A.E. Ershov, S.V. Karpov, S.P. Polyutov, P.N. Semina, 2016, published in Kolloidnyi Zhurnal, 2016, Vol. 78, No. 4, pp. 417–425.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Gerasimov, V.S., Ershov, A.E., Karpov, S.V. et al. Optimization of photothermal methods for laser hyperthermia of malignant cells using bioconjugates of gold nanoparticles. Colloid J 78, 435–442 (2016). https://doi.org/10.1134/S1061933X16040050

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1134/S1061933X16040050

Search

Navigation