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Applying of the information technologies for toxicity analysis of organic xenobiotics from an international list of the Baltic Sea pollutants

  • Water Quality and Protection: Environmental Aspects
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Abstract

The main focus of this work was to evaluate the capabilities of information technology to establish the biological activity of organic xenobiotics on the example of hazardous substances from the list of Helsinki commission (HELCOM) aimed at protecting the marine environment of the Baltic Sea from negative impact. These methodological approaches will be used in future for the preliminary assessment of the toxicity of new xenobiotics revealed in Baltic waters.

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References

  1. Barenboim, G.M., Biologically active substances, New Principles of Search, M.: Nauka, 1986, p. 364.

    Google Scholar 

  2. Danilov-Daniliyan, V.I., Poroikov, V.V., Chiganova, M.A., Kozlov, M.N., Filimonov, D.A., and Barenboim, G.M., Identification of new types of xenobiotics with pharmaceutical activity in the water sources of the Moscow city, Water Supply Sanitary Equipment, 2013, Vol. 10, pp. 17–25.

    Google Scholar 

  3. Filimonov, D.A. and Poroikov, V.V., Prognosis of biological activity spectrum of organic compounds, Russ. Chem. J., 2006, Vol. 50, No. 2, pp. 66–75.

    Google Scholar 

  4. Harmful substances, Helsinki Convention, Annex I, http:// wwwhelcomru/helsinki_convention/applications.

  5. Helcom objective with regard to hazardous substances, http://wwwhelcomfi/Recommendations/en_GB/ rec19_5/.

  6. HELCOM, Regional executive organization-operator for the implementation of programs, projects and solutions HELCOM. http://wwwhelcomru/about.

  7. Lagunin, A., Zakharov, A., Filimonov, D., and Poroikov, V., QSAR Modelling of Rat Acute Toxicity on the Basis of PASS Prediction, Mol. Inform., 2011, Vol. 30, nos. 2–3, pp. 241–250.

    Article  Google Scholar 

  8. Poroikov, V. and Filimonov, D., PASS: Prediction of biological activity spectra for substances, Predictive Toxicol., Helma, C., Ed., Taylor & Francis, 2006, pp. 459–478.

    Google Scholar 

  9. Poroikov, V.V., Druzhilovsky, D.S., Rudik, A.V., Khudyakov, D.V., and Filimonov, D.A., Web-services for biological activity prognosis via Internet, Book of Math. Congress “Men and drug”, Moscow: OJSC “Shcherbinskaya typography”, 2012, p. 415.

    Google Scholar 

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Authors and Affiliations

  1. Institute of Water Problems, Russian Academy of Sciences, ul. Gubkina 3, Moscow, 119333, Russia

    A. S. Safonova, M. A. Chiganova & G. M. Barenboim

Authors
  1. A. S. Safonova
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  2. M. A. Chiganova
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  3. G. M. Barenboim
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Correspondence to G. M. Barenboim.

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Safonova, A.S., Chiganova, M.A. & Barenboim, G.M. Applying of the information technologies for toxicity analysis of organic xenobiotics from an international list of the Baltic Sea pollutants. Water Resour 43, 377–394 (2016). https://doi.org/10.1134/S0097807816020159

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  • DOI: https://doi.org/10.1134/S0097807816020159

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