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Immobilization of microbial cells for biotechnological production: Modern solutions and promising technologies

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Abstract

A review of modern works on the creation of biotechnological processes using cells immobilized on different carriers is presented. General material requirements are given for for immobilization mainly performed by absorption and mechanical fixation methods. The results of studies on cell immobilization are considered, and an analysis of the materials and methods used is given. Some potential and active applications of systems with immobilized cells for biotechnological productions are described. A review of possible variants of technological solutions for bioreactors loaded by carriers with immobilized cells is also presented. It was demonstrated that the use of such a load allows constructive bioreactor solutions of significantly more efficient.

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Abbreviations

CL:

cultural liquid

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  1. National Research Center, Kurchatov Institute, Moscow, 123182, Russia

    P. M. Gotovtsev, K. V. Gorin, V. V. Butylin, G. U. Badranova, Z. B. Namsaraev, A. V. Komova & R. G. Vasilov

  2. State Research Institute of Genetics and Selection of Industrial Microorganisms, Moscow, 117545, Russia

    E. Yu. Yuzbasheva, N. I. Perkovskaya, E. B. Mostova & S. P. Sineokii

  3. Michurinsk State Agrarian University, Michurinsk, Tambov oblast, 393760, Russia

    N. I. Rudneva

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  1. P. M. Gotovtsev
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  2. E. Yu. Yuzbasheva
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  3. K. V. Gorin
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  4. V. V. Butylin
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  5. G. U. Badranova
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  6. N. I. Perkovskaya
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  7. E. B. Mostova
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  8. Z. B. Namsaraev
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  9. N. I. Rudneva
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  10. A. V. Komova
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  11. R. G. Vasilov
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  12. S. P. Sineokii
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Correspondence to P. M. Gotovtsev.

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Original Russian Text © P.M. Gotovtsev, E.Yu. Yuzbasheva, K.V. Gorin, V.V. Butylin, G.U. Badranova, N.I. Perkovskaya, E.B. Mostova, Z.B. Namsaraev, N.I. Rudneva, A.V. Komova, R.G. Vasilov, S.P. Sineokii, 2015, published in Biotekhnologiya, 2015, No. 2, pp. 8–21.

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Gotovtsev, P.M., Yuzbasheva, E.Y., Gorin, K.V. et al. Immobilization of microbial cells for biotechnological production: Modern solutions and promising technologies. Appl Biochem Microbiol 51, 792–803 (2015). https://doi.org/10.1134/S0003683815080025

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  • DOI: https://doi.org/10.1134/S0003683815080025

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