Abstract
Mitochondrial DNA (mtDNA) in cells is organized in nucleoids containing DNA and various proteins. This review discusses questions of organization and structural dynamics of nucleoids as well as their protein components. The structures of mt-nucleoid from different organisms are compared. The currently accepted model of nucleoid organization is described and questions needing answers for better understanding of the fine mechanisms of the mitochondrial genetic apparatus functioning are discussed.
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Abbreviations
- mtDNA:
-
mitochondrial DNA
- mt genome:
-
mitochondrial genome
References
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Original Russian Text © A. A. Kolesnikov, 2016, published in Biokhimiya, 2016, Vol. 81, No. 10, pp. 1322–1331.
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Kolesnikov, A.A. The mitochondrial genome. The nucleoid. Biochemistry Moscow 81, 1057–1065 (2016). https://doi.org/10.1134/S0006297916100047
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DOI: https://doi.org/10.1134/S0006297916100047