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Synthesis, characterization, and antimicrobial activity of new benzofuran derivatives

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Abstract

A novel series of (5-substituted-1-benzofuran-2-yl)(2,4-substituted phenyl)methanones (4a–4i) have been prepared by the Knoevenagel condensation of (5-substituted-1-benzofuran-2-yl)(2,4-substituted phenyl)methanone (3a–3i) with Meldrum’s acid. The structures of the synthesized compounds were characterized by different spectroscopic techniques. All newly synthesized compounds were screened for antimicrobial activity.

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Authors and Affiliations

  1. Department of P. G. Studies and Research in Industrial Chemistry, Jnana Sahyadri, Kuvempu University Shankaraghatta, Shivamogga, Karnataka, 577451, India

    R. Kenchappa, Yadav D. Bodke, M. Aruna Sindhe & M. Giridhar

  2. Department of P. G. Studies and Research in Biotechnology and Bioinformatics, Jnana Sahyadri, Kuvempu University, Shankaraghatta, Karnataka, 577451, India

    Sandeep Telkar

Authors
  1. R. Kenchappa
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  2. Yadav D. Bodke
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  3. Sandeep Telkar
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  4. M. Aruna Sindhe
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  5. M. Giridhar
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Corresponding author

Correspondence to Yadav D. Bodke.

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Kenchappa, R., Bodke, Y.D., Telkar, S. et al. Synthesis, characterization, and antimicrobial activity of new benzofuran derivatives. Russ J Gen Chem 86, 2827–2836 (2016). https://doi.org/10.1134/S107036321612046X

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  • DOI: https://doi.org/10.1134/S107036321612046X

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