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Azimuth-invariant mueller-matrix differentiation of the optical anisotropy of biological tissues

  • Physical and Geometrical Optics
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Abstract

A Mueller-matrix model is proposed for analysis of the optical anisotropy of protein networks of optically thin nondepolarizing layers of biological tissues with allowance for birefringence and dichroism. The model is used to construct algorithms for reconstruction of coordinate distributions of phase shifts and coefficient of linear dichroism. Objective criteria for differentiation of benign and malignant tissues of female genitals are formulated in the framework of the statistical analysis of such distributions. Approaches of evidence-based medicine are used to determine the working characteristics (sensitivity, specificity, and accuracy) of the Mueller-matrix method for the reconstruction of the parameters of optical anisotropy and show its efficiency in the differentiation of benign and malignant tumors.

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References

  1. M. H. Smith, P. Burke, A. Lompado, E. Tanner, and L. W. Hillman, Proc. SPIE—Int. Soc. Opt. Eng. 3991, 210 (2000).

    Google Scholar 

  2. M. H. Smith, Proc. SPIE—Int. Soc. Opt. Eng. 4257, 82 (2001).

    ADS  Google Scholar 

  3. Yu. A. Ushenko, Ukr. J. Phys. Opt. 6, 63 (2005).

    Article  Google Scholar 

  4. T. T. Tower, Biophys. J. 81, 2954 (2001).

    Article  ADS  Google Scholar 

  5. J. M. Bueno and J. Jaronski, Ophthalmol. Physiol. Opt. 21, 384 (2001).

    Article  Google Scholar 

  6. J. M. Bueno and F. Vargas-Martin, Appl. Opt. 41, 116 (2002).

    Article  ADS  Google Scholar 

  7. J. M. Bueno and M. C. W. Campbell, Ophthalmol. Physiol. Opt. 23, 109 (2003).

    Article  Google Scholar 

  8. T. T. Tower and R. T. Tranquillo, Biophys. J. 81, 2964 (2001).

    Article  Google Scholar 

  9. M. Shribak and R. Oldenbourg, Appl. Opt. 42, 3009 (2003).

    Article  ADS  Google Scholar 

  10. O. V. Angelsky, A. G. Ushenko, D. N. Burkovets, and Y. A. Ushenko, J. Biomed. Opt. 10, 014010 (2005).

    Article  ADS  Google Scholar 

  11. A. Y. Bekshaev, O. V. Angelsky, S. G. Hanson, and C. Y. Zenkova, Phys. Rev. A 86, 023847 (2012).

    Article  ADS  Google Scholar 

  12. O. V. Angelsky, P. V. Polyanskii, and C. V. Felde, Opt. Photonics News 23, 25 (2012).

    Article  ADS  Google Scholar 

  13. Y. A. Ushenko, J. Biomed. Opt. 16, 066006 (2011).

    Article  ADS  Google Scholar 

  14. O. V. Angelsky, S. G. Hanson, A. P. Maksimyak, and P. P. Maksimyak, Opt. Express 13, 4396 (2005).

    Article  ADS  Google Scholar 

  15. Yu. A. Ushenko, Yu. Yu. Tomka, and A. V. Dubolazov, Opt. Spektrosk. 110(6), 814 (2011).

    Article  ADS  Google Scholar 

  16. O. V. Angelsky, A. G. Ushenko, D. N. Burkovets, and Yu. A. Ushenko, Opt. Appl. 32, 591 (2002).

    Google Scholar 

  17. Y. A. Ushenko, I. Z. Misevich, O. Y. Telenga, Y. Y. Tomka, and A. O. Karachevtsev, Optical Memory and Neural Networks (Information Optics) 20, 59 (2011).

    Article  Google Scholar 

  18. Y. O. Ushenko, Y. Y. Tomka, I. Z. Misevitch, V. V. Istratyy, and O. I. Telenga, Opt. Eng. 50, 039001 (2011).

    Article  ADS  Google Scholar 

  19. O. V. Angelsky, A. G. Ushenko, D. N. Burkovets, Yu. A. Ushenko, R. Jozwicki, and K. Patorski, Opt. Appl. 32, 603 (2002).

    Google Scholar 

  20. Yu. A. Ushenko, Yu. Ya. Tomka, A. V. Dubolazov, and O. Yu. Telen’ga, Quantum Electron. 41, 273 (2011).

    Article  ADS  Google Scholar 

  21. Y. A. Ushenko, Opto-electron. Rev. 19, 425 (2011).

    Article  ADS  Google Scholar 

  22. Y. A. Ushenko, Opto-electron. Rev. 19, 333 (2011).

    Article  ADS  Google Scholar 

  23. Yu. A. Ushenko, J. Innov. Opt. Health Sci. 5, 1150001 (2012).

    Article  Google Scholar 

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Authors and Affiliations

  1. Chernovtsy National University, Chernovtsy, 58012, Ukraine

    V. A. Ushenko

  2. Department of Optics and Spectroscopy, Chernovtsy National University, Chernovtsy, 58012, Ukraine

    M. I. Sidor

  3. Bukovina State Medical University, Chernovtsy, 58000, Ukraine

    Yu. F. Marchuk, N. V. Pashkovskaya & D. R. Andreichuk

Authors
  1. V. A. Ushenko
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  2. M. I. Sidor
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  3. Yu. F. Marchuk
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  4. N. V. Pashkovskaya
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  5. D. R. Andreichuk
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Corresponding author

Correspondence to Yu. F. Marchuk.

Additional information

Original Russian Text © V.A. Ushenko, M.I. Sidor, Yu.F. Marchuk, N.V. Pashkovskaya, D.R. Andreichuk, 2014, published in Optika i Spektroskopiya, 2014, Vol. 117, No. 1, pp. 159–165.

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Ushenko, V.A., Sidor, M.I., Marchuk, Y.F. et al. Azimuth-invariant mueller-matrix differentiation of the optical anisotropy of biological tissues. Opt. Spectrosc. 117, 152–157 (2014). https://doi.org/10.1134/S0030400X14070248

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  • DOI: https://doi.org/10.1134/S0030400X14070248

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