Abstract—
Barium-substituted tricalcium phosphates containing 0.43 and 4.28 wt % barium have been prepared via mechanochemical activation and precipitation from aqueous solutions, followed by calcination. We have determined the phase composition of the synthesized compounds and the specific surface area of the powders and evaluated their sinterability. The synthesized powders were sintered at temperatures of 1100, 1150, and 1200°C to give ceramic samples. We studied linear shrinkage of the samples during sintering, determined the bending strength of the ceramics, and examined their microstructure. The biological properties of the ceramics were studied in vitro using mesenchymal stem cells isolated from tooth pulp. The results demonstrate that the ceramics are not cytotoxic and can be used in reconstructive bone tissue surgery.
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Funding
This work was supported by the Russian Federation Ministry of Science and Higher Education, state research target no. 075-00328-21-00.
The in vitro studies were supported through the state research target no. 075-00381-21-00.
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Translated by O. Tsarev
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Fadeeva, I.V., Ryzhov, A.P., Titov, D.D. et al. Barium-Substituted Tricalcium Phosphate Ceramics. Inorg Mater 58, 317–324 (2022). https://doi.org/10.1134/S0020168522030037
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DOI: https://doi.org/10.1134/S0020168522030037