Fluorescence optical tomography with a priori information

Murat Guven; Birsen Yazici; Vasilis Ntziachristos

doi:10.1117/12.715073

14 February 2007 Fluorescence optical tomography with a priori information

Murat Guven, Birsen Yazici, Vasilis Ntziachristos

Proceedings Volume 6431, Multimodal Biomedical Imaging II; 643107 (2007) https://doi.org/10.1117/12.715073
Event: SPIE BiOS, 2007, San Jose, California, United States

Abstract

In this work, we discuss the incorporation of a priori information into the inverse problem formulation for fluorescence optical tomography. In this respect, we first formulate the inverse problem in the optimization framework which allows the incorporation of a priori information about the solution and its gradient. Then, we consider the variational problem, which is equivalent to the optimization problem and prove the existence and uniqueness of the solution. Finally, we discuss the design of the functions that incorporate the a priori information into the inverse problem formulation and present a model problem to illustrate the design procedure.

Citation Download Citation

Murat Guven, Birsen Yazici, and Vasilis Ntziachristos "Fluorescence optical tomography with a priori information", Proc. SPIE 6431, Multimodal Biomedical Imaging II, 643107 (14 February 2007); https://doi.org/10.1117/12.715073

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