Towards deep super-resolution coherent Raman scattering microscopy in scattering media (Conference Presentation)

Julien Guilbert; Awoke A. Negash; Simon Labouesse; Sylvain Gigan; Hilton Barbosa de Aguiar; Anne Sentenac

doi:10.1117/12.2544868

10 March 2020 Towards deep super-resolution coherent Raman scattering microscopy in scattering media (Conference Presentation)

Julien Guilbert, Awoke A. Negash, Simon Labouesse, Sylvain Gigan, Hilton Barbosa de Aguiar, Anne Sentenac

Author Affiliations +

Proceedings Volume 11252, Advanced Chemical Microscopy for Life Science and Translational Medicine; 112520A (2020) https://doi.org/10.1117/12.2544868
Event: SPIE BiOS, 2020, San Francisco, California, United States

Abstract

We present a simulation of stimulated Raman scattering that could make deep super resolution imaging possible with chemical selectivity and relatively low power levels. For this, we directly use speckles as a structured illumination pattern in a coherent Raman scattering processes, in particular Stimulated Raman Scattering. Using off-the-shelf conjugate gradient-based algorithm, we demonstrate that the method enables super-resolution better than conventional raster scanning techniques.

Conference Presentation

Citation Download Citation

Julien Guilbert, Awoke A. Negash, Simon Labouesse, Sylvain Gigan, Hilton Barbosa de Aguiar, and Anne Sentenac "Towards deep super-resolution coherent Raman scattering microscopy in scattering media (Conference Presentation)", Proc. SPIE 11252, Advanced Chemical Microscopy for Life Science and Translational Medicine, 112520A (10 March 2020); https://doi.org/10.1117/12.2544868

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