Quantification of hemoglobin and its derivatives in oral cancer diagnosis by diffuse reflectance spectroscopy

Udayakumar Kaniyappan; Einstein Gnanatheepam; Prakasarao Aruna; Koteeswaran Dornadula; Singaravelu Ganesan

doi:10.1117/12.2255874

17 February 2017 Quantification of hemoglobin and its derivatives in oral cancer diagnosis by diffuse reflectance spectroscopy

Udayakumar Kaniyappan, Einstein Gnanatheepam, Prakasarao Aruna, Koteeswaran Dornadula, Singaravelu Ganesan

Author Affiliations +

Proceedings Volume 10060, Optical Biopsy XV: Toward Real-Time Spectroscopic Imaging and Diagnosis; 100601F (2017) https://doi.org/10.1117/12.2255874
Event: SPIE BiOS, 2017, San Francisco, California, United States

Abstract

Cancer is one of the most common threat to human beings and it increases at an alarming level around the globe. In recent years, due to the advancements in opto-electronic technology, various optical spectroscopy techniques have emerged to assess the photophysicochemical and morphological conditions of normal and malignant tissues in micro as well as in macroscopic scale. In this regard, diffuse reflectance spectroscopy is considered to be the simplest, cost effective and rapid technique in diagnosis of cancerous tissues. In the present study, the hemoglobin concentration in normal and cancerous oral tissues was quantified and subsequent statistical analysis has been carried out to verify the diagnostic potentiality of the technique.

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Udayakumar Kaniyappan, Einstein Gnanatheepam, Prakasarao Aruna, Koteeswaran Dornadula, and Singaravelu Ganesan "Quantification of hemoglobin and its derivatives in oral cancer diagnosis by diffuse reflectance spectroscopy", Proc. SPIE 10060, Optical Biopsy XV: Toward Real-Time Spectroscopic Imaging and Diagnosis, 100601F (17 February 2017); https://doi.org/10.1117/12.2255874

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