Diagnosis potential of near infrared Mueller Matrix imaging for colonic adenocarcinoma

Jianfeng Wang; Wei Zheng; Kan Lin; Zhiwei Huang

doi:10.1117/12.2212074

7 March 2016 Diagnosis potential of near infrared Mueller Matrix imaging for colonic adenocarcinoma

Jianfeng Wang, Wei Zheng, Kan Lin, Zhiwei Huang

Proceedings Volume 9698, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIV; 96980X (2016) https://doi.org/10.1117/12.2212074
Event: SPIE BiOS, 2016, San Francisco, California, United States

Abstract

Mueller matrix imaging along with polar decomposition method was employed for the colonic adenocarcinoma detection by polarized light in the near-infrared spectral range (700–1100 nm). A high-speed (<5s) Muller matrix imaging system with dual-rotating waveplates was developed. 16 (4 by 4) full Mueller matrices of the colonic tissues (i.e., normal and caner) were acquired. Polar decomposition was further implemented on the 16 images to derive the diattentuation, depolarization, and the retardance images. The decomposed images showed clear margin between the normal and adenocarcinomaous colon tissue samples. The work shows the potential of near-infrared Mueller matrix imaging for the early diagnosis and detection of malignant lesions in the colon.

Citation Download Citation

Jianfeng Wang, Wei Zheng, Kan Lin, and Zhiwei Huang "Diagnosis potential of near infrared Mueller Matrix imaging for colonic adenocarcinoma", Proc. SPIE 9698, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIV, 96980X (7 March 2016); https://doi.org/10.1117/12.2212074

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