Identify paraffin-embedded brain glioma using terahertz pulsed spectroscopy

Ze-ren Li; Kun Meng; Tu-nan Chen; Tao Chen; Li-guo Zhu; Qiao Liu; Zhao Li; Fei Li; Sen-cheng Zhong; Hua Feng; Jian-heng Zhao

doi:10.1117/12.2075165

9 January 2015 Identify paraffin-embedded brain glioma using terahertz pulsed spectroscopy

Ze-ren Li, Kun Meng, Tu-nan Chen, Tao Chen, Li-guo Zhu, Qiao Liu, Zhao Li, Fei Li, Sen-cheng Zhong, Hua Feng, Jian-heng Zhao

Author Affiliations +

Proceedings Volume 9444, International Seminar on Photonics, Optics, and Its Applications (ISPhOA 2014); 94440P (2015) https://doi.org/10.1117/12.2075165
Event: International Seminar on Photonics, Optics, and Applications 2014, 2014, Sanur, Bali, Indonesia

Abstract

The refractive indices, absorption coefficients and complex dielectric constants spectra of paraffin-embedded brain glioma and normal brain tissues have been measured by a terahertz time domain spectroscopy (THz-TDS) system in the range of 0.2 – 2.0 THz. The spectral differences between glioma and normal brain tissues were obtained. Our results indicate that, compared with normal tissue, glioma had higher refractive index, absorption coefficient, and dielectric constant. Based on these results, the suitable frequency components for different methods of glioma imaging (intensity imaging, coherent imaging and terahertz pulsed imaging) are analyzed.

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Ze-ren Li, Kun Meng, Tu-nan Chen, Tao Chen, Li-guo Zhu, Qiao Liu, Zhao Li, Fei Li, Sen-cheng Zhong, Hua Feng, and Jian-heng Zhao "Identify paraffin-embedded brain glioma using terahertz pulsed spectroscopy", Proc. SPIE 9444, International Seminar on Photonics, Optics, and Its Applications (ISPhOA 2014), 94440P (9 January 2015); https://doi.org/10.1117/12.2075165

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