Plasmon saturation induced super-resolution imaging

Hsuan Lee; Tung-Yu Su; Yasuo Yonemaru; Ming-Ying Lee; Masahito Yamanaka; Ko-Fan Huang; Satoshi Kawata; Katsumasa Fujita; Shi-Wei Chu

doi:10.1117/12.2003815

21 February 2013 Plasmon saturation induced super-resolution imaging

Hsuan Lee, Tung-Yu Su, Yasuo Yonemaru, Ming-Ying Lee, Masahito Yamanaka, Ko-Fan Huang, Satoshi Kawata, Katsumasa Fujita, Shi-Wei Chu

Author Affiliations +

Proceedings Volume 8597, Plasmonics in Biology and Medicine X; 85970P (2013) https://doi.org/10.1117/12.2003815
Event: SPIE BiOS, 2013, San Francisco, California, United States

Abstract

Conventionally, super-resolution imaging is achieved by manipulating the on/off switching of fluorophores, or by saturation of fluorescence emission. To prevent the photobleaching of fluorophores, we demonstrate novel superresolution imaging based on saturation of scattering from plasmonic particles, for the first time. With spectral studies, we have confirmed the saturation is directly linked to surface plasmon resonance effect. With the aid of saturation excitation microscopy, plus field concentration due to nonlinear plasmon resonance, we have achieved optical resolution below 80-nm based on scattering. Our study will open up a completely new paradigm for super-resolution microscopy.

Citation Download Citation

Hsuan Lee, Tung-Yu Su, Yasuo Yonemaru, Ming-Ying Lee, Masahito Yamanaka, Ko-Fan Huang, Satoshi Kawata, Katsumasa Fujita, and Shi-Wei Chu "Plasmon saturation induced super-resolution imaging", Proc. SPIE 8597, Plasmonics in Biology and Medicine X, 85970P (21 February 2013); https://doi.org/10.1117/12.2003815

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