Scan timing considerations in indicator dilution analysis of dynamic CT image sequences

Erik Leo Ritman M.D.

doi:10.1117/12.174395

1 May 1994 Scan timing considerations in indicator dilution analysis of dynamic CT image sequences

Erik Leo Ritman M.D.

Proceedings Volume 2168, Medical Imaging 1994: Physiology and Function from Multidimensional Images; (1994) https://doi.org/10.1117/12.174395
Event: Medical Imaging 1994, 1994, Newport Beach, CA, United States

Abstract

Dynamic computed tomography (CT) provides the advantages of sampling in many regions within an organ where a sampling catheter could not be introduced and eliminates superposition. However, dynamic CT is generally slow. An important aspect of the indicator dilution curve generation is the sampling frequency and sample duration. The indicator dilution curves generated with a CT scanner must behave like the `conventional' indicators. The contrast agent passes sequentially through the heart chambers and in doing so the duration of the bolus increases and the peak opacification of the bolus diminishes. The pattern of progressive dispersal of the dilution curve, somewhat in proportion to the duration of the curve's transit along the circulation, conveys something about the structure-to-function relationship of the circulation through which the indicator passes. The standard deviation to mean transit time relationship in the aortic root appears to be along a different regression line than does that relationship in the myocardium.

Citation Download Citation

Erik Leo Ritman M.D. "Scan timing considerations in indicator dilution analysis of dynamic CT image sequences", Proc. SPIE 2168, Medical Imaging 1994: Physiology and Function from Multidimensional Images, (1 May 1994); https://doi.org/10.1117/12.174395

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