DNA sequencing by multiple capillaries that form a waveguide

Harbans S. Dhadwal; Mark A. Quesada; F. William Studier

doi:10.1117/12.273541

7 May 1997 DNA sequencing by multiple capillaries that form a waveguide

Harbans S. Dhadwal, Mark A. Quesada, F. William Studier

Proceedings Volume 2980, Advances in Fluorescence Sensing Technology III; (1997) https://doi.org/10.1117/12.273541
Event: BiOS '97, Part of Photonics West, 1997, San Jose, CA, United States

Abstract

A 12-capillary prototype electrophoresis system for DNA sequencing has been constructed. Laser illumination is introduced into an optical waveguide that is formed by an array of individual capillaries that serve both as the optical elements of the periodic array and as the channels containing sieving media for electrophoresis. A theoretical framework and experimental data will be presented to illustrate the viability of this approach.

Citation Download Citation

Harbans S. Dhadwal, Mark A. Quesada, and F. William Studier "DNA sequencing by multiple capillaries that form a waveguide", Proc. SPIE 2980, Advances in Fluorescence Sensing Technology III, (7 May 1997); https://doi.org/10.1117/12.273541

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