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Kinetics of diarrhetic shellfish poisoning toxins, okadaic acid, dinophysistoxin-1, pectenotoxin-6 and yessotoxin in scallops Patinopecten yessoensis

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Abstract

Four toxins, okadaic acid (OA), dinophysistoxin-1 (DTX1), pectenotoxin-6 (PTX6), and yessotoxin (YTX), all associated with diarrhetic shellfish poisoning (DSP), were administered via syringe to Scallops Patinopecten yessoensis and their distribution in the hepatopancreas, adductor muscle, and combined other tissues (mantle, gill, gonad) was analyzed by liquid chromatography-mass spectrometry. Toxins exclusively remained in the hepatopancreas irrespective of the injection site, adductor muscle or hepatopancreas. When injected into hepatopancreas, OA, DTX1, and YTX were metabolized to 7-O-palmitoylOA, 7-O-palmitoylDTX1 and 45-hydroxyyessotoxin (45OH-YTX), respectively. Such metabolic changes were insignificant when toxins were injected into the adductor muscle. The residual ratio for each toxin in the hepatopancreas was less than 20%. Mortalities of scallops treated with PTX6 were lower than those treated with other toxins.

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Authors and Affiliations

  1. Tohoku National Fisheries Research Institute, 985-0001, Shiogama, Miyagi, Japan

    Toshiyuki Suzuki

  2. Japan Food Research Laboratories, Tama, 206-0025, Tokyo, Japan

    Tomoji Igarashi, Masatoshi Watai, Megumi Suzuki, Eri Ogiso & Takeshi Yasumoto

  3. Marine Environment Research Station, Kagawa University, 761-0130, Kita, Kagawa, Japan

    Kazuhiko Ichimi

Authors
  1. Toshiyuki Suzuki
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  2. Tomoji Igarashi
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  3. Kazuhiko Ichimi
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  4. Masatoshi Watai
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  5. Megumi Suzuki
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  6. Eri Ogiso
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  7. Takeshi Yasumoto
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Correspondence to Toshiyuki Suzuki.

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Suzuki, T., Igarashi, T., Ichimi, K. et al. Kinetics of diarrhetic shellfish poisoning toxins, okadaic acid, dinophysistoxin-1, pectenotoxin-6 and yessotoxin in scallops Patinopecten yessoensis . Fish Sci 71, 948–955 (2005). https://doi.org/10.1111/j.1444-2906.2005.01049.x

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  • DOI: https://doi.org/10.1111/j.1444-2906.2005.01049.x

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