Glycyl-L-Leucyl-L-Tyrosine Dihydrate 2-Propanol Solvate

The asymmetric unit (C₁₇H₂₅N₃O₅.C₃H₈O.2H₂O) consists of two crystallographically independent peptide molecules, A and B, with different conformations, χ½ being trans and gauche⁻ for the Leu residues in molecules A and B, respectively. The backbone conformation of both peptide molecules resembles that of the β-pleated sheet arrangement found in proteins. Comparison with two other structures containing the tripeptide Gly L-Leu-L-Tyr reveals almost identical molecular conformations, and in one instance also a common packing pattern.