Emergent global oscillations in heterogeneous excitable media: The example of pancreatic β cells

Julyan H. E. Cartwright
Phys. Rev. E 62, 1149 – Published 1 July 2000
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Abstract

Using the standard van der Pol–FitzHugh–Nagumo excitable medium model, I demonstrate a generic mechanism, diversity, that provokes the emergence of global oscillations from individually quiescent elements in heterogeneous excitable media. This mechanism may be operating in the mammalian pancreas, where excitable β cells, quiescent when isolated, are found to oscillate when coupled, despite the absence of a pacemaker region.

  • Received 31 March 1999

DOI:https://doi.org/10.1103/PhysRevE.62.1149

©2000 American Physical Society

Authors & Affiliations

Julyan H. E. Cartwright*

  • Laboratono de Estudios Cristalográficos, IACT (CSIC-UGR), E-18071 Granada, Spain

  • *Email address: julyan@galiota.uib.es; URL: http://formentor.uib.es/julyan

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Vol. 62, Iss. 1 — July 2000

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