Additive scaling law for structural organization of chromatin in chicken erythrocyte nuclei

E. G. Iashina, E. V. Velichko, M. V. Filatov, W. G. Bouwman, C. P. Duif, A. Brulet, and S. V. Grigoriev
Phys. Rev. E 96, 012411 – Published 19 July 2017

Abstract

Small-angle neutron scattering (SANS) on nuclei of chicken erythrocytes demonstrates the cubic dependence of the scattering intensity Q3 in the range of momentum transfer Q103102nm1. Independent spin-echo SANS measurements give the spin-echo function, which is well described by the exponential law in a range of sizes (3×102)(3×104) nm. Both experimental dependences reflect the nature of the structural organization of chromatin in the nucleus of a living cell, which corresponds to the correlation function γ(r)=ln(ξ/r) for r<ξ, where ξ=(3.69±0.07)×103 nm, the size of the nucleus. It has the specific scaling property of the logarithmic fractal γ(r/a)=γ(r)+ln(a), i.e., the scaling down by a gives an additive constant to the correlation function, which distinguishes it from the mass fractal, which is characterized by multiplicative constant.

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  • Received 19 January 2017

DOI:https://doi.org/10.1103/PhysRevE.96.012411

©2017 American Physical Society

Physics Subject Headings (PhySH)

Condensed Matter, Materials & Applied PhysicsPhysics of Living Systems

Authors & Affiliations

E. G. Iashina1,2, E. V. Velichko3, M. V. Filatov1, W. G. Bouwman3, C. P. Duif3, A. Brulet4, and S. V. Grigoriev1,2

  • 1Petersburg Nuclear Physics Institute, Gatchina, St. Petersburg 188300, Russia
  • 2Saint Petersburg State University, Ulyanovskaya 1, St. Petersburg 198504, Russia
  • 3Delft University of Technology, Mekelweg 15, 2629 JB Delft, Netherlands
  • 4Leon Brillouin Laboratory, CEA Saclay, 91191 Gif sur Yvette Cedex, France

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Issue

Vol. 96, Iss. 1 — July 2017

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