SOME RECENT DEVELOPMENTS IN THE X-RAY STUDY OF PROTEINS AND RELATED STRUCTURES
This extract was created in the absence of an abstract.
Excerpt
This paper falls naturally into three sections, for the reason that over the last few months we have been interested in three main topics; and on the principle that almost anything about proteins is interesting, even at a protein symposium, there is no very great difficulty about either offering or accepting them together.
I. X-rays and the Stoichiochemistry of Proteins
A troublesome aspect of protein structure which has always been at the back of one's mind, and is now very much to the forefront, has to do with the stoichiometrical relations, or otherwise, between the constituent amino acid residues. Experimentally, the problem has proved so full of obstacles that until quite recently only the vaguest ideas emerged, for the available chemical analyses were both contradictory and incomplete. Vickery, Block (1) and others had demonstrated certain fairly constant ratios between the proportions of the basic residues, for instance, but it was...
