THE QUANTITATIVE COMPOSITION OF DEOXYPENTOSE NUCLEIC ACIDS AS RELATED TO THE NEWLY PROPOSED STRUCTURE1
This extract was created in the absence of an abstract.
Excerpt
The structure for DNA which Watson and Crick (1953) have proposed could provide a basis for certain regularities in the composition of DNA's which we have been observing for some time. Of course this does not mean that the structure is necessarily correct, but I should like to point out how the analytical results are consistent with it, and do indeed appear to demand specific pairing of a sort similar to that which Dr. Watson has described.
It was first observed by Chargaff (1951) that the ratios of adenine to thymine and of guanine to cytosine in DNA from a number of sources is relatively constant and close to unity. These regularities were especially clearly brought out by the composition of the DNA's of a series of insect viruses (Wyatt, 1952). These were analyzed by hydrolysis of the whole viruses in perchloric acid followed by paper chromatography, and for the...
Footnotes
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↵1 Contribution No. 110, Forest Biology Division, Science Service, Department of Agriculture, Ottawa, Canada.
