Abstract
Acinetobacter baumannii is a clinically relevant pathogen which causes multi-drug resistant, hospital-acquired infections and is a top priority target for antibiotic development. Cryo-EM structures of the A. baumannii F1Fo-ATP synthase in three conformational states reveal unique features, which represent attractive sites for the development of novel therapeutics.
One sentence summary Structure of Acinetobacter baumannii ATP synthase
Competing Interest Statement
The authors have declared no competing interest.
Abbreviations
- ATP
- Adenosine-5’-triphosphate
- cryo-EM
- electron cryo-microscopy
- MDR
- multi drug resistance
- (XDR)
- extensively drug resistance
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