Diverse functions of WD40 repeat proteins in histone recognition
Abstract
WD40 repeat proteins have been shown to bind the histone H3 tail at the center of their β-propeller structure. In contrast, in this issue of Genes & Development, Song and colleagues (pp. 1313–1318) demonstrate that the WD40 repeat protein p55 binds a structured region of H4 through a novel binding pocket on the side of β-propeller, illustrating a diversity of histone recognition by WD40 repeat proteins.
Keywords
Footnotes
-
↵1 Corresponding author.
↵1 E-MAIL jlw{at}stowers-institute.org; FAX (816) 926-4692.
-
Article is online at http://www.genesdev.org/cgi/doi/10.1101/gad.1676208.
- Copyright © 2008, Cold Spring Harbor Laboratory Press
