The Structure and Function of Myoblast Adherons
This extract was created in the absence of an abstract.
Excerpt
Because many macromolecules found in growth-conditioned media are derived from or are related to those on the cell surface (Doljanski and Kapeller 1976; Schubert 1976; Baum et al. 1977; Kao et al. 1977), an examination of these molecules may help characterize the outer plasma membrane and adhesive mechanisms of the cell. For example, materials released into the culture medium by myoblasts and fibroblasts adhere to the surface of culture dishes and promote cell-substratum adhesion (Moore 1976; Schubert and LaCorbiere 1980a). The extracellular matrix elaborated in vivo and by many cultured cells also contains molecules that promote cellular adhesion (Hawkes and Wang 1982). Similar molecules are likely to play a major role in the development of the nervous system.
The observation that material in growth-conditioned medium promotes cellular adhesion was made initially with chick neural retina cells (Lilien and Moscona 1967; McClay and Moscona 1974). Although several activities that may be...
