Regular Research ArticleDevelopment of a Short Form of the Severe Impairment Battery
Section snippets
Subjects
SIB data were available from two samples (total N = 191). Sample 1 consisted of 87 individuals living in Pittsburgh, PA (United States). Twenty-six individuals were participants in the clinical study “Serotonergic Pharmacotherapy for the treatment of Agitation in patients with Dementia” (SPAD), which has been previously described.21 The remaining 61 individuals in Sample 1 were subjects from the Alzheimer's Disease Research Center (ADRC) at the University of Pittsburgh Medical Center. A
RESULTS
The mean age (standard deviation [SD]) of the American sample was 77.1 (10.5) years, and the mean age of the French sample was 87.2 (7.8) years. The majority of subjects were women (American sample: 60.8%; French sample: 86.5%). The mean MMSE scores for the American sample and the French sample were 7.7 (4.8) and 5.7 (3.4), respectively, and for the SIB scores were 71.87 (18.34) and 58.38 (26.86), respectively. The two groups were significantly different in age (t[189] = 7.4; p <0.001),
DISCUSSION
There are very few scales that are appropriate for the assessment of cognitive functioning in patients with severe dementia. The significant cognitive and behavioral dysfunction typically seen in patients with scores in the lower half of the MMSE range (i.e., <15) presents a challenge to the accurate and reliable measurement of cognitive abilities. There are three scales that have been shown to be particularly useful with this population: the SIB, The Severe Cognitive Impairment Profile (SCIP),
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The French sample was recruited with the help of Marie-Pierre Hervy, M.D., at Kremlin Bicêtre Hospital; Anne-Sophie Rigaud, M.D., Ph.D., at Broca Hospital; Laurent Teillier, M.D., at Sainte Perine Hospital; François Piette, M.D., at Charles Foix Hospital, as well as Michel Roudier, M.D., Ph.D., and Jamal al-Aloucy, at Charles-Richet Hospital.
The research reported in this article was supported in the United States by grants from the National Institute on Aging (AG05133) and the National Institute of Mental Health (MH59666, MH65416, and RR-00056) and in France by INSERM and by the Lundbeck Laboratory, with partial support from Eisai Laboratory.