European Journal of Gastroenterology & Hepatology

Accession Number<strong>00042737-200110000-00016</strong>.
AuthorFarkas, Henriette a; Harmat, George b; Kaposi, Pal N. c; Karadi, Istvan d; Fekete, Bela e; Fust, George f; Fay, Kalman g; Vass, Aniko g; Varga, Lilian h
Institution(a)Kutvolgyi Clinical Centre, Allergology and Angio-oedema Outpatient Clinic, (d)Kutvolgyi Clinical Centre,(e)3(rd) Department of Internal Medicine, (f)3(rd) Department of Internal Medicine, Research Laboratory, and (g)Department of Radiology, Semmelweis University, Budapest, Hungary; (b)Madarasz Street Children's Hospital, Budapest, Hungary; (c)National Institute of Rheumatology & Physiotherapy, Department of Radiology, Budapest, Hungary; (h)National Institute of Haematology and Immunology, Budapest, Hungary
TitleUltrasonography in the diagnosis and monitoring of ascites in acute abdominal attacks of hereditary angioneurotic oedema.[Article]
SourceEuropean Journal of Gastroenterology & Hepatology. 13(10):1225-1230, October 2001.
AbstractBackground: Hereditary angioneurotic oedema (HAE) is a rare cause of ascites. As acute abdominal attacks of the disease can mimic surgical emergencies, prompt and accurate diagnosis is essential. This study was undertaken to evaluate the usefulness of serial abdominal ultrasound (US) examinations.

Patients and methods: Seventy patients with HAE were followed up for almost a decade. All patients presenting with an acute oedematous attack underwent abdominal US, which was then repeated 24 and 48 h after appropriate therapy.

Results: Twenty-two acute oedematous attacks with abdominal complaints severe enough to justify hospital admission occurred in the study population. Abdominal US performed during the attack showed oedematous thickening of the intestinal wall in 80% of cases and invariably demonstrated the presence of free peritoneal fluid in all patients. Rapid symptomatic relief achieved by treatment was accompanied by the significant regression of US abnormalities.

Conclusions: Transitory ascites demonstrated by abdominal US is a clue to the diagnosis of an acute abdominal attack of HAE. The possibility of HAE should always be considered whenever unexplained abdominal pain recurs with or without ascites.

(C) 2001 Lippincott Williams & Wilkins, Inc.