Model for Influences of Magnetic Fields on Intracellular Calcium Oscillations

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2009 Chinese Physical Society and IOP Publishing Ltd
, , Citation Zhang Yu-Hong et al 2009 Commun. Theor. Phys. 52 168 DOI 10.1088/0253-6102/52/1/36

0253-6102/52/1/168

Abstract

Based on the model of the two calcium stores developed by Goldbeter, the influence of external magnetic field on the calcium concentration has been discussed. We believe that the cell membrane is a major site of interaction for extremely-low-frequency (ELF) electromagnetic fields, and the permeability of ions can be changed with the changing electromagnetic fields. It is shown that magnetic field initiates intracellular calcium oscillation with a threshold in flux density, and that the calcium oscillations do not occur if the density of magnetic field is below the threshold. The results of theoretical calculation are consistent with that of the experiment. The intracellular free calcium concentrations of different cells exposed to the same magnetic fields are different from each other. It is indicated that the different behaviors such as oscillation, rise and invariability of calcium concentration are associated with the sort of cells.

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10.1088/0253-6102/52/1/36