Paper The following article is Open access

The influence of hydrodynamic conditions and chamber geometry on the analytical signal from integrated biochips

, , , and

Published under licence by IOP Publishing Ltd
, , Citation N A Esikova et al 2018 J. Phys.: Conf. Ser. 1135 012021 DOI 10.1088/1742-6596/1135/1/012021

1742-6596/1135/1/012021

Abstract

The integration of a biochip with a PDMS fluidic chamber was accomplished. The advantage of dynamic analyte flows, versus static ones, was experimentally demonstrated. This was further clarified by numerical simulation including the approximate mathematical solutions modelling the convective motion and the biotinylated antibody-streptavidin interaction. The possibility of influenza virus A/California/07/09 (H1N1)pdm09 detection by the proposed method was demonstrated.

Export citation and abstract BibTeX RIS

Content from this work may be used under the terms of the Creative Commons Attribution 3.0 licence. Any further distribution of this work must maintain attribution to the author(s) and the title of the work, journal citation and DOI.

Please wait… references are loading.
10.1088/1742-6596/1135/1/012021