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Risk Factors for Nosocomial Infective Endocarditis in Patients with Methicillin-Resistant Staphylococcus Aureus Bacteremia

Published online by Cambridge University Press:  21 June 2016

Ron-Bin Hsu
Ron-Bin Hsu*
Affiliation:
Department of Surgery, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan, Republic of China
*
National Taiwan University Hospital, No. 7, Chung-Shan S. Rd., Taipei, Taiwan 100, Republic of China.ronbin@ha.mc.ntu.edu.tw
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Abstract

Background and Objective:

Nosocomial infections caused by methicillin-resistant Staphylococcus aureus (MRSA) are increasing. Only a few studies of MRSA infective endocarditis have been conducted, and none have reported its risk factors. We sought to determine the host-related risk factors for infective endocarditis in patients with nosocomial MRSA bacteremia.

Setting:

A 2,000-bed, university-affiliated, tertiary-care hospital.

Patients:

Thirty-one patients with nosocomial MRSA infective endocarditis between October 1996 and May 2003.

Design:

A retrospective chart review was conducted. Data were compared with those from a control group of patients with nosocomial MRSA bacteremia. Logistic regression was used to identify independent risk factors for nosocomial infective endocarditis.

Results:

Compared with patients who had nosocomial MRSA bacteremia and no infective endocarditis, patients who had infective endocarditis had a higher incidence of chronic liver disease and a lower incidence of immunodeficiency. The risk of developing infective endocarditis was approximately 10% for patients with nosocomial MRSA bacteremia.

Conclusion:

Patients with MRSA bacteremia and underlying chronic liver disease were prone to infective endocarditis. (Infect Control Hosp Epidemiol 2005;26:654-657)

Type
Original Articles
Information
Infection Control & Hospital Epidemiology , Volume 26 , Issue 7 , July 2005 , pp. 654 - 657
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2005

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