Hostname: page-component-848d4c4894-x5gtn Total loading time: 0 Render date: 2024-05-01T00:15:05.763Z Has data issue: false hasContentIssue false
  • English
  • Français

The estimation of whole-body zinc and Zn turnover in rheumatoid and osteoarthritis using 65Zn tracer

Published online by Cambridge University Press:  09 March 2007

A. C. Kennedy ,
R. G. Bessent ,
P. Davis  and
P. M. G. Reynolds
A. C. Kennedy
Affiliation:
Centre for Rheumatic Diseases, University Department of Medicine, Glasgow Royal Infirmary, Glasgow G4 0EH and Department of Nuclear Medicine, Royal Infirmary and West of Scotland Health Boards, Department of Clinical Physics and Bio-Engineering, Glasgow
R. G. Bessent
Affiliation:
Centre for Rheumatic Diseases, University Department of Medicine, Glasgow Royal Infirmary, Glasgow G4 0EH and Department of Nuclear Medicine, Royal Infirmary and West of Scotland Health Boards, Department of Clinical Physics and Bio-Engineering, Glasgow
P. Davis
Affiliation:
Centre for Rheumatic Diseases, University Department of Medicine, Glasgow Royal Infirmary, Glasgow G4 0EH and Department of Nuclear Medicine, Royal Infirmary and West of Scotland Health Boards, Department of Clinical Physics and Bio-Engineering, Glasgow
P. M. G. Reynolds
Affiliation:
Centre for Rheumatic Diseases, University Department of Medicine, Glasgow Royal Infirmary, Glasgow G4 0EH and Department of Nuclear Medicine, Royal Infirmary and West of Scotland Health Boards, Department of Clinical Physics and Bio-Engineering, Glasgow
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

1. A method of estimating whole-body zinc, and Zn balances using a two-compartment model in combination with whole-body counting of 65Zn, is described. The method is applied to patients with rheumatoid and osteoarthritis.

2. The results suggested that there was not a wide variation in whole-body Zn and Zn turnover in individuals with these two diseases and no clearcut difference between patients with one or the other.

Type
Papers of direct relevance to Clinical and Human Nutrition
Information
British Journal of Nutrition , Volume 40 , Issue 1 , July 1978 , pp. 115 - 123
Copyright
Copyright © The Nutrition Society 1978

References

Bennett, R. M., Holt, P. J. & Lewis, S. M. (1974). Ann. rheum. Dis. 33, 147.CrossRefGoogle Scholar
Bonebrake, R. A., McCall, J. T., Hunder, G. G. & Polley, H. F. (1972). Proc. Staff Meet, Mayo Clin. 47, 746.Google Scholar
Bradley, J. V. (1968). In Distribution-Free Statistical Tests, p. 105. New Jersey: Prentice-Hall.Google Scholar
Flear, C. T., Cooke, W. T. & Quinton, A. (1957). Lancet i, 458.CrossRefGoogle Scholar
Freireich, E. J., Ross, J. F., Bayles, T. B., Emerson, C. P. & Finch, S. C. (1957). J. clin. Invest. 36, 1043.CrossRefGoogle Scholar
Graig, F. A. & Siegel, E. (1960). Proc. Soc. exp. Biol. Med. 104, 391.CrossRefGoogle Scholar
Henkin, R. I. & Aamodt, R. L. (1975). Lancet i, 1379.CrossRefGoogle Scholar
Hume, R. & Weyers, E. (1971). J. clin. Path. 24, 234.CrossRefGoogle Scholar
Hussain, S. L. & Bessent, R. G. (1974). In Clinical Applications of Zinc Metabolism, p. 168 [Pories, W. J., Strain, W. H., Hsu, J. M. and Woosley, R. L., editors]. Springfield, Illinois: Thomas.Google Scholar
Kennedy, A. C., Fell, G. S., Rooney, P. J., Stevens, W. H., Dick, W. C. & Buchanan, W. W. (1975). Scand. J. Rheumatol. 4, 243.CrossRefGoogle Scholar
Kennedy, A. C., Smith, D. A., Anton, H. C. & Buchanan, W. W. (1975). Scand. J. Rheumatol. 4, 209.CrossRefGoogle Scholar
Lombeck, I., Schnippering, H. G., Ritzl, F., Feinemdegen, L. E. & Bremner, H. J. (1975). Lancet i, 855.CrossRefGoogle Scholar
Matthews, C. M. E. (1971). In Radioisotopes in Medical Diagnosis. [Belcher, E. H. and Vetter, H., editors]. London: Butterworths.Google Scholar
Pace, N. & Rathbun, E. N. (1945). J. biol. Chem. 158, 685.CrossRefGoogle Scholar
Peaston, R. T. (1973). Med. Lab. Technol. 30, 249.Google Scholar
Richmond, C. R., Furchner, J. E., Trafton, G. A. & Langham, W. H. (1962). Hlth Phys. 8, 481.CrossRefGoogle Scholar
Ropes, M. W., Bennet, G. A., Cobb, S., Jacox, R. & Jessar, A. R. (1959). Ann. rheum. Dis. 18, 49.Google Scholar
Ross, J. F., Ebaugh, F. G. & Talbot, T. R. (1958). Trans. Ass. Am. Physns 71, 322.Google Scholar
Samachson, J., Dennis, J., Fowler, R. & Schmitz, A. (1967). Biochim. biophys. Acta 148, 767.CrossRefGoogle Scholar
Simkin, P. A. (1976). Lancet ii, 539.CrossRefGoogle Scholar
Spencer, H., Rosoff, B., Feldstein, A., Cohn, S. H. & Gusmano, E. (1965). Radiat. Res. 24, 432.CrossRefGoogle Scholar
Spencer, H. V., Rosoff, B., Lewin, I. & Samachson, J. (1966). In Zinc Metabolism, p. 339 [Prasad, A. S., editor]. Springfield, Ill.: C. C. Thomas.Google Scholar
Vallee, B. L. (1959). Physiol. Res. 39, 443.Google Scholar
Vallee, B. L. (1964). In Mineral Metabolism, p. 443 [Comar, C. L. and Bronner, F., editors]. London: Academic Press.Google Scholar
Vallee, B. L. & Gibson, J. G. (1948). J. biol. Chem. 176, 445.CrossRefGoogle Scholar
Walshe, J. M. (1956). Lancet, i, 25.CrossRefGoogle Scholar
Walshe, J. M. (1963). Clin. Sci. 25, 405.Google Scholar
Walshe, J. M. (1967). Brain 90, 149.CrossRefGoogle Scholar
Walshe, J. M. (1970). Br. J. Hosp. Med. 4, 91.Google Scholar
Widdowson, E. M., McCance, R. A. & Spray, C. M. (1951). Clin. Sci. 10, 113.Google Scholar