Journal of Biological Chemistry
Volume 294, Issue 8, February 2019, Pages 2815-5640
MetabolismAn extracellular histidine-containing motif in the zinc transporter ZIP4 plays a role in zinc sensing and zinc-induced endocytosis in mammalian cellsExtracellular zinc sensor motif in ZIP4 endocytosis
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open access
metal homeostasis
endocytosis
zinc
transport
trafficking
cellular import
extracellular sensing
metal toxicity
protein trafficking
ZIP4
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This work was supported by National Institutes of Health Grants DK110195 (to B.-E. K.) and DK66333 (to M. J. P.). The authors declare that they have no conflicts of interest with the contents of this article.The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.
This article contains Figs. S1–S5.
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Present address: Beckman Coulter, Chaska, MN 55318.