Journal of Biological Chemistry
Volume 285, Issue 49, 3 December 2010, Pages 38524-38533
Molecular BiophysicsTwo Independent Histidines, One in Human Prolactin and One in Its Receptor, Are Critical for pH-dependent Receptor Recognition and Activation*
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open access
Cytokine Action
JAK Kinase
STAT Transcription Factor
Surface Plasmon Resonance (SPR)
X-ray Crystallography
Human Prolactin
Human Prolactin Receptor
pH Dependence
PKA
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This work was supported, in whole or in part, by National Institutes of Health Grant RO1 CA 108992 (to M. E. H.).
The on-line version of this article (available at http://www.jbc.org) contains supplemental Tables 1–2, Figs. 1–5, and data.
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Supported by National Institutes of Health Training Grant T32-HL007974-07.
© 2010 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology.