Journal of Biological Chemistry
Volume 290, Issue 36, 4 September 2015, Pages 22030-22048
NeurobiologyInhibition of N-Methyl-d-aspartate-induced Retinal Neuronal Death by Polyarginine Peptides Is Linked to the Attenuation of Stress-induced Hyperpolarization of the Inner Mitochondrial Membrane Potential*
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apoptosis
mitochondrial membrane potential
N-methyl-d-aspartate receptor (NMDA receptor, NMDAR)
necrosis (necrotic death)
neuroprotection
retina
retinal ganglion cells
Cited by (0)
- *
This work was supported, in whole or in part, by National Institutes of Health Grants R21 NS061176 (to D. J. G., M. R. S., and J. M.) from NINDS, Grants R01 EY014430 (to D. J. G.) and GM63021 (to M. R. S.) from NEI, NEI Core Grants P30EY0468 (Wayne State University) and P20-EY00700 (University of Michigan), and NHLBI Training Grant T32HL120822 (to C. S.). J. M. owns shares in Angelus Therapeutics. No materials or support were received from this company. United States patent application entitled “Neuroprotective Composition and Method of Use” (United States Patent Application WO2013158739) has been filed by Brown University, with D. J. G. and J. M. listed as inventors.
© 2015 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology.