Journal of Biological Chemistry
Signal TransductionFunctional Cross-talk between Ras and Rho Pathways: A Ras-SPECIFIC GTPase-ACTIVATING PROTEIN (p120RasGAP) COMPETITIVELY INHIBITS THE RhoGAP ACTIVITY OF DELETED IN LIVER CANCER (DLC) TUMOR SUPPRESSOR BY MASKING THE CATALYTIC ARGININE FINGER*
Cited by (0)
- *
This work was supported in part by the German Research Foundation (Deutsche Forschungsgemeinschaft (DFG)) through the Collaborative Research Center 974 (SFB 974) “Communication and Systems Relevance during Liver Injury and Regeneration,” the International Research Training Group 1902 (IRGT1902), and Project Grant AH 92/5-1; the National Genome Research Network Plus program of the German Ministry of Science and Education (Bundesministerium für Bildung und Forschung Grant 01GS08100); and the International North Rhine-Westphalia Research School BioStruct granted by the Ministry of Innovation, Science and Research of the State North Rhine-Westphalia, the Heinrich Heine University of Düsseldorf, and the Entrepreneur Foundation at the Heinrich Heine University of Düsseldorf.
- 6
M. Jaiswal, E. Amin, and R. Dvorsky, unpublished data.
- 1
Present address: Structural Biology Group, Max Planck Inst. for Molecular Physiology, Otto-Hahn-Strasse 11, 44227 Dortmund, Germany.
- 2
Present address: Inst. of Physical Biology, Heinrich Heine University, 40255 Düsseldorf, Germany.
- 3
Supported by the DFG Heisenberg program.
- 5
The abbreviations used are:
- GAP
GTPase-activating protein
- DLC
deleted in liver cancer
- SH
Src homology
- SAM
sterile α motif
- START
steroidogenic acute regulatory related lipid transfer
- aa
amino acids
- tamra
tetramethylrhodamine
- aSEC
analytical size exclusion chromatography
- ITC
isothermal titration calorimetry.