Journal of Biological Chemistry
Volume 286, Issue 43, 28 October 2011, Pages 37196-37206
Gene Regulation5-Aza-2′-deoxycytidine Activates Iron Uptake and Heme Biosynthesis by Increasing c-Myc Nuclear Localization and Binding to the E-boxes of Transferrin Receptor 1 (TfR1) and Ferrochelatase (Fech) Genes*
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open access
DNA Methylation
Erythropoiesis
Heme
Protein DNA-Interaction
Transcription Regulation
5-Aza-CdR
TfR1
c-Myc
Myelodysplastic Syndromes
Cited by (0)
- *
This work was supported by National Basic Research Program of China (973 program) Grants 2012CB934000, 2011CB933400, and 2010CB912802 and National Natural Science Foundation of China Grants 30900278 and 10979011.
The on-line version of this article (available at http://www.jbc.org) contains supplemental Figs. S4 and S5.
- 2
Recipient of a Senior Research Fellowship from the National Health and Medical Research Council of Australia.
- 1
Both authors contributed equally to this work.
© 2011 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology.