Isolation and Hypoglycemie Activity of Anemarans A, B, C and D, Glycans of Anemarrhena asphodeloides Rhizomes1

Michiko Takahashi; Chohachi Konno; Hiroshi Hikino

doi:10.1055/s-2007-969417

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Planta Med 1985; 51(2): 100-102
DOI: 10.1055/s-2007-969417

Research Articles

Isolation and Hypoglycemie Activity of Anemarans A, B, C and D, Glycans of Anemarrhena asphodeloides Rhizomes¹

Michiko Takahashi, Chohachi Konno, Hiroshi Hikino

Pharmaceutical Institute, Tohoku University, Aoba-yama, Sendai, Japan

1 Antidiabetes drugs, Part 7. Also Part 86 in the series on the validity of the Oriental medicines

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Publication History

1984

1984

Publication Date:
26 February 2007 (online)

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Abstract

An aqueous methanol/water extract of the Oriental crude drug “chimo”, Anemarrhena asphodeloides rhizomes, exhibited a marked hypoglycemie activity on dosing to mice. Fractionation of the extract, by monitoring the pharmacological activity, resulted in isolation of four glycans, anamerans A, B, C and D. These constituents displayed significant hypoglycemie effects in normal and alloxan-produced hyperglycemie mice.

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