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Synthesis 1992; 1992(6): 582-586
DOI: 10.1055/s-1992-26169
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A Practical Method for N-Acylation of Bornane-2,10-sultam and 2-Oxazolidinones

Catriona Thom* , Philip Kocieński
  • *Department of Chemistry, The University, Southampton, SO9 5NH, England
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Publication History

Publication Date:
17 September 2002 (online)

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The N-trimethylsilyl derivatives of (+)-bornane-2,10-sultam (10,10-dimethyl-5-thia-4-azatricyclo[5.2.1.03,7]decane 5,5-dioxide) and (R)-4-benzyl-2-oxazolidinone and 4-methyl-5-phenyl-2-oxazo-lidinone react with acid chlorides in refluxing benzene in the presence of copper(II) chloride to give the corresponding N-acyl derivatives in good yield.

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