Endoscopy 2024; 56(S 02): S458
DOI: 10.1055/s-0044-1783855
Abstracts | ESGE Days 2024
ePoster

Endoscopic submucosal dissection for early gastrointestinal cancers in India: A retrospective analysis of a single-center experience for clinical outcomes and future directions

P. Inavolu
1   AIG Hospitals, Hyderabad, India
,
M. Ramchandani
1   AIG Hospitals, Hyderabad, India
,
Z. Nabi
1   AIG Hospitals, Hyderabad, India
,
A. Gahra
1   AIG Hospitals, Hyderabad, India
,
S. Darisetty
1   AIG Hospitals, Hyderabad, India
,
R. Ram
1   AIG Hospitals, Hyderabad, India
,
N. R. Duvvur
1   AIG Hospitals, Hyderabad, India
› Author Affiliations
 

Aims Our aim is to identify the success rate of endoscopic submucosal dissection (ESD) in early gastrointestinal cancers. The success of ESD is identified using R0 resection and Enbloc dissection for various early gastrointestinal cancers and to report the finding of our experience with ESD from India.

Methods ESD was performed for patients with suspected Early GI cancers who fulfilled the criteria for resection. Curative resection and R0 resection was calculated after excluding submucosal lesion (Neuroendocrine tumors & spindle cell lesions)

Results Total 117 lesions were resected in 115 patients, 18(15.3%) were in esophagus, 24 (20.5%) in stomach, 26 (22.2%) in duodenum and 49 (41.8%) were present in colon. Mean size of lesion was 2.7+-1.6cm in esophagus, 2.87±1.18cm in stomach, 1.48±0.3cm in duodenum,3.63±1.98cm in colon with enbloc resection in each being 100%, 83.33%, 99.2%, 81.8% respectively. Overall Enbloc resection rate was 91.07%. Overall Curative resection & R0 resection was found to be 96.35% and 94.8% respectively in total 81 lesions. Individual R0 and Curative resection in each region were- Oesophagus-100%, 100%; stomach- 100%, 93.75%; Duodenum-100%, 100%; colon- 79.2%, 91.66%.

Conclusions The study provides valuable insight into outcomes of ESD in India for early GI cancers being minimally invasive yet potentially curative therapeutic option guiding us to incorporate ESD as a standard of care in Indian guidelines for management of early GI cancers. [1]



Publication History

Article published online:
15 April 2024

© 2024. European Society of Gastrointestinal Endoscopy. All rights reserved.

Georg Thieme Verlag KG
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  • References

  • 1 De Marco MO, Tustumi F, Brunaldi VO, Resende RH, Matsubayashi CO, Baba ER, Chaves DM, Bernardo WM, de Moura EGH.. Prognostic factors for ESD of early gastric cancers: a systematic review and meta-analysis. Endosc Int Open 2020; 8 (09) E1144-E1155 DOI: 10.1055/a-1201-3089.. Epub 2020 Aug 31 PMID: 32904802; PMCID: PMC7458740