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CC BY-NC-ND 4.0 · Asian J Neurosurg 2022; 17(03): 480-484
DOI: 10.1055/s-0042-1756624
Case Report

Perioperative Considerations in a Patient with Kleine–Levin Syndrome Undergoing a Neurosurgical Procedure under General Anesthesia

Wesley Rajaleelan
1   Department of Anesthesia and Pain Management, University Health Network, University of Toronto, Toronto Western Hospital, Toronto, Ontario, Canada
2   Department of Anesthesia and Pain Management, Women's College Hospital, Toronto, Ontario, Canada
,
Tumul Chowdhury
1   Department of Anesthesia and Pain Management, University Health Network, University of Toronto, Toronto Western Hospital, Toronto, Ontario, Canada
2   Department of Anesthesia and Pain Management, Women's College Hospital, Toronto, Ontario, Canada
,
Rebecca Moga
1   Department of Anesthesia and Pain Management, University Health Network, University of Toronto, Toronto Western Hospital, Toronto, Ontario, Canada
2   Department of Anesthesia and Pain Management, Women's College Hospital, Toronto, Ontario, Canada
,
Carla Todaro
1   Department of Anesthesia and Pain Management, University Health Network, University of Toronto, Toronto Western Hospital, Toronto, Ontario, Canada
2   Department of Anesthesia and Pain Management, Women's College Hospital, Toronto, Ontario, Canada
,
Gelareh Zadeh
3   Department of Neurosurgery, University Health Network, University of Toronto, Toronto Western Hospital, Toronto, Ontario, Canada
,
Justin Wang
3   Department of Neurosurgery, University Health Network, University of Toronto, Toronto Western Hospital, Toronto, Ontario, Canada
,
Mandeep Singh
1   Department of Anesthesia and Pain Management, University Health Network, University of Toronto, Toronto Western Hospital, Toronto, Ontario, Canada
2   Department of Anesthesia and Pain Management, Women's College Hospital, Toronto, Ontario, Canada
4   Toronto Sleep and Pulmonary Centre, Toronto, Ontario, Canada
› Author Affiliations Funding Support was provided solely from institutional and/or departmental sources. MS is supported by the Canadian Anesthesiologists Society Career Scientist Award, as well as the Merit Awards Program from the Department of Anesthesia at the University of Toronto.
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Abstract

Kleine–Levin syndrome (KLS) is a rare central disorder of daytime hypersomnolence and is often characterized by a relapsing and remitting course, recurrent episodes of excessive sleep lasting from 12 to 20 hours a day, and symptoms including hyperphagia, hallucinations, derealization, disorientation, and hypersexuality. There are numerous perioperative considerations in dealing with KLS that include challenges during induction of anesthesia, delayed emergence, postoperative sleep disorders, and delirium. However, due to its rare occurrence, the anesthetic considerations of KLS remain poorly described. This case report outlines the anesthetic considerations and management of a young female patient with KLS who underwent transnasal excision of a trigeminal schwannoma under general anesthesia.

Keywords

Kleine–Levin syndrome - narcolepsy - sleep disorders

Informed Consent

The patient provided written and informed consent for publication of this case report and the consent is available upon request.




Publication History

Article published online:
07 October 2022

© 2022. Asian Congress of Neurological Surgeons. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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