J Knee Surg 2023; 36(06): 605-612
DOI: 10.1055/s-0041-1741395
Original Article

Comparison of Femoral Triangle Block in Combination with IPACK to Local Periarticular Injection in Total Knee Arthroplasty

Xiang Li#
1   Department of Orthopedics, Naval Medical University, Changzheng Hospital, Shanghai, China
,
Yuanyuan Wang#
2   School of Life Sciences, Bengbu Medical College, Bengbu, Anhui, China
,
Yancheng Chen#
1   Department of Orthopedics, Naval Medical University, Changzheng Hospital, Shanghai, China
,
Jiatian Qian
1   Department of Orthopedics, Naval Medical University, Changzheng Hospital, Shanghai, China
,
Shiao Li
1   Department of Orthopedics, Naval Medical University, Changzheng Hospital, Shanghai, China
,
Song Chen
3   Department of Orthopedics, The General Hospital of Western Theater Command, Chengdu, Sichuan, China
,
Peiliang Fu
1   Department of Orthopedics, Naval Medical University, Changzheng Hospital, Shanghai, China
› Author Affiliations

Abstract

Objective This article studied the efficacy of two different analgesic methods after unilateral primary total knee arthroplasty (TKA) to find an effective analgesic method.

Methods A randomized, double-blind, placebo, parallel, and controlled study was performed to evaluate the benefits of combining the femoral triangle block (FTB) and the interspace between the popliteal artery and the capsule of the posterior knee (IPACK). Forty patients diagnosed with knee osteoarthritis and underwent unilateral primary TKA with FTB and IPACK were divided grouped into the experimental group, and 40 patients undergoing TKA with intra-articular cocktail analgesic mixture local injection were grouped into the control group. All patients received the patient-controlled anesthesia pump for analgesia at postoperative 48 hours. The main indexes were postoperative knee joint rest and activity pain (visual analog scale) and muscle strength of the affected limb; secondary indexes were anesthetic consumption, total morphine consumption, range of motion, and complications (such as postoperative nausea and vomiting [PONV]).

Results There was no significant difference in the general data of each treatment group. Compared with the conventional group, the quadriceps muscle strength of the combined FTB and IPACK group was higher with significant statistical differences after surgery (p < 0.05). At postoperative 2, 6, 12, 24, 48, and 72 hours, active pain was better than in the conventional group (p < 0.05). Resting pain was significantly smaller than the traditional group only at postoperative 2, 6, 12, and 48 hours (p < 0.05). Morphine consumption, anesthetics consumption, and hospitalization time were lower than the conventional group, the difference being statistically significant. There were no significant differences between the two groups in postoperative wound healing, infection incidence, blood pressure, heart rate, rash, respiratory depression, deep vein thrombosis, and urinary retention. There were also no significant differences in PONV (p > 0.05).

Conclusion Combining FTB and IPACK significantly increased the quadriceps muscle in patients, together with relieving early pain and reducing the amount of anesthetic consumption at different postoperative intervals.

# Xiang Li, Yuanyuan Wang, and Yancheng Chen contributed equally to this work.




Publication History

Received: 09 February 2021

Accepted: 16 November 2021

Article published online:
10 February 2022

© 2022. Thieme. All rights reserved.

Thieme Medical Publishers, Inc.
333 Seventh Avenue, 18th Floor, New York, NY 10001, USA

 
  • References

  • 1 Yano T, Imaizumi T, Matsu-Ura H, Takahashi T. Relationship between dexamethasone added to periarticular anesthetic infiltration and postoperative nausea and vomiting following total knee arthroplasty under general anesthesia: a retrospective observational study. JA Clin Rep 2020; 6 (01) 66
  • 2 Davies AF, Segar EP, Murdoch J, Wright DE, Wilson IH. Epidural infusion or combined femoral and sciatic nerve blocks as perioperative analgesia for knee arthroplasty. Br J Anaesth 2004; 93 (03) 368-374
  • 3 Sigirci A. Pain management in total knee arthroplasty by intraoperative local anesthetic application and one-shot femoral block. Indian J Orthop 2017; 51 (03) 280-285
  • 4 Korean KS. Korean Knee Society. Guidelines for the management of postoperative pain after total knee arthroplasty. Knee Surg Relat Res 2012; 24 (04) 201-207
  • 5 Li JW, Ma YS, Xiao LK. Postoperative pain management in total knee arthroplasty. Orthop Surg 2019; 11 (05) 755-761
  • 6 Gao F, Ma J, Sun W, Guo W, Li Z, Wang W. Adductor canal block versus femoral nerve block for analgesia after total knee arthroplasty: a systematic review and meta-analysis. Clin J Pain 2017; 33 (04) 356-368
  • 7 Ohgoshi Y, Matsutani M, Kubo EN. Use of IPACK block with continuous femoral triangle block for total knee arthroplasty: a clinical experience. J Clin Anesth 2019; 54: 52-54
  • 8 Lee HJ, Bach JR, DeLisa JA. Medial femoral cutaneous nerve conduction. Am J Phys Med Rehabil 1995; 74 (04) 305-307
  • 9 Runge C, Bjørn S, Jensen JM. et al. The analgesic effect of a popliteal plexus blockade after total knee arthroplasty: a feasibility study. Acta Anaesthesiol Scand 2018; DOI: 10.1111/aas.13145.
  • 10 Jung DW, Shon WY, Seo SS, Kim OG, Lee IS. Comparison of the postoperative analgesic effect for infiltration between the popliteal artery and the capsule of the posterior knee and that of periarticular multimodal drug injection in total knee arthroplasty: retrospective study in the immediate postoperative period. Knee Surg Relat Res 2020; 32 (01) 1
  • 11 Fu P, Wu Y, Wu H, Li X, Qian Q, Zhu Y. Efficacy of intra-articular cocktail analgesic injection in total knee arthroplasty - a randomized controlled trial. Knee 2009; 16 (04) 280-284
  • 12 Sankineani SR, Reddy ARC, Eachempati KK, Jangale A, Gurava Reddy AV. Comparison of adductor canal block and IPACK block (interspace between the popliteal artery and the capsule of the posterior knee) with adductor canal block alone after total knee arthroplasty: a prospective control trial on pain and knee function in immediate postoperative period. Eur J Orthop Surg Traumatol 2018; 28 (07) 1391-1395
  • 13 Kandarian B, Indelli PF, Sinha S. et al. Implementation of the IPACK (infiltration between the popliteal artery and capsule of the knee) block into a multimodal analgesic pathway for total knee replacement. Korean J Anesthesiol 2019; 72 (03) 238-244
  • 14 Runge C, Børglum J, Jensen JM. et al. The analgesic effect of obturator nerve block added to a femoral triangle block after total knee arthroplasty: a randomized controlled trial. Reg Anesth Pain Med 2016; 41 (04) 445-451
  • 15 Berninger MT, Friederichs J, Leidinger W. et al. Effect of local infiltration analgesia, peripheral nerve blocks, general and spinal anesthesia on early functional recovery and pain control in unicompartmental knee arthroplasty. BMC Musculoskelet Disord 2018; 19 (01) 249
  • 16 Bjørn S, Nielsen TD, Moriggl B, Hoermann R, Bendtsen TF. Anesthesia of the anterior femoral cutaneous nerves for total knee arthroplasty incision: randomized volunteer trial. Reg Anesth Pain Med 2019; rapm-2019-100904
  • 17 Thobhani S, Scalercio L, Elliott CE. et al. Novel regional techniques for total knee arthroplasty promote reduced hospital length of stay: an analysis of 106 patients. Ochsner J 2017; 17 (03) 233-238
  • 18 Jules- Elysee KM, Wilfred SE, Memtsoudis SG. et al. Steroid modulation of cytokine release and desmosine levels in bilateral total knee replacement: a prospective, double-blind, randomized controlled trial. J Bone Joint Surg Am 2012; 94 (23) 2120-2127
  • 19 Si HB, Yang TM, Zeng Y. et al. Correlations between inflammatory cytokines, muscle damage markers and acute postoperative pain following primary total knee arthroplasty. BMC Musculoskelet Disord 2017; 18 (01) 265