Download PDF
J Neurol Surg Rep 2014; 75(01): e27-e32
DOI: 10.1055/s-0033-1358378
Case Report
Georg Thieme Verlag KG Stuttgart · New York

Unique Presentation of Cerebellopontine Angle Choroid Plexus Papillomas: Case Report and Review of the Literature

Mark Anderson
1   School of Medicine, The George Washington University School of Medicine, Washington, District of Columbia, United States
,
Parker Babington
2   Department of Neurosurgery, The George Washington University, Washington, District of Columbia, United States
,
Reza Taheri
3   Department of Radiology, The George Washington University, Washington, Washington, District of Columbia, United States
,
Mairo Diolombi
4   Department of Pathology, The George Washington University, Washington, District of Columbia, United States
,
Jonathan H. Sherman
2   Department of Neurosurgery, The George Washington University, Washington, District of Columbia, United States
› Author Affiliations
Further Information

Publication History

27 October 2012

01 September 2013

Publication Date:
12 December 2013 (online)

   Permissions and Reprints

Abstract

Objectives We present the case of a choroid plexus papilloma (CPP) in the cerebellopontine angle (CPA), describe the different appearances of CPPs with a variety of imaging techniques, and discuss the differential diagnosis of CPA tumors.

Participant and Design We report the case of a 52-year-old woman with headache, tinnitus, and unilateral hearing impairment whose preoperative magnetic resonance imaging revealed a heterogeneously enhancing CPA mass that extended into the internal auditory canal.

Main Outcome Measures, Results, and Conclusion The preoperative imaging appearance of the lesion was most consistent with that of a schwannoma. Postoperative histopathologic examination found the tumor to be a CPP with cuboidal epithelial cells overlying fibrovascular stroma. CPPs are rare benign central nervous system neoplasms arising from choroid plexus epithelium. The most common site of presentation is in the fourth ventricle in adults and the lateral ventricles in children. CPPs rarely occur in the CPA, and when they do, clinical-radiologic diagnosis is difficult due to both the rarity of this presentation and to nonspecific radiological features.

Keywords

cerebellopontine angle - choroid plexus papilloma
 

  • References

  • 1 McGirr SJ, Ebersold MJ, Scheithauer BW, Quast LM, Shaw EG. Choroid plexus papillomas: long-term follow-up results in a surgically treated series. J Neurosurg 1988; 69 (6) 843-849
    CrossrefPubMedGoogle Scholar
  • 2 Chari G, Dhaygude A, Kulkarni MV, Patkar SV, Kalgutkar A. Choroid plexus papilloma. Indian Pediatr 1994; 31 (10) 1305-1308
    PubMedGoogle Scholar
  • 3 Wolff JE, Sajedi M, Brant R, Coppes MJ, Egeler RM. Choroid plexus tumours. Br J Cancer 2002; 87 (10) 1086-1091
    CrossrefPubMedGoogle Scholar
  • 4 Strojan P, Popović M, Surlan K, Jereb B. Choroid plexus tumors: a review of 28-year experience. Neoplasma 2004; 51 (4) 306-312
    PubMedGoogle Scholar
  • 5 Enomoto H, Mizuno M, Katsumata T, Doi T. Intracranial metastasis of a choroid plexus papilloma originating in the cerebellopontine angle region: a case report. Surg Neurol 1991; 36 (1) 54-58
    CrossrefPubMedGoogle Scholar
  • 6 Furuya K, Sasaki T, Saito N, Atsuchi M, Kirino T. Primary large choroid plexus papillomas in the cerebellopontine angle: radiological manifestations and surgical management. Acta Neurochir (Wien) 1995; 135 (3–4) 144-149
    CrossrefPubMedGoogle Scholar
  • 7 Khoddami M, Gholampour Shahaboddini R. Choroid plexus papilloma of the cerebellopontine angle. Arch Iran Med 2010; 13 (6) 552-555
    PubMedGoogle Scholar
  • 8 Kumar R, Achari G, Benerji D, Jain VK, Chhabra DK. Choroid plexus papillomas of the cerebellopontine angle. Neurol India 2002; 50 (3) 352-358
    PubMedGoogle Scholar
  • 9 Talacchi A, De Micheli E, Lombardo C, Turazzi S, Bricolo A. Choroid plexus papilloma of the cerebellopontine angle: a twelve patient series. Surg Neurol 1999; 51 (6) 621-629
    CrossrefPubMedGoogle Scholar
  • 10 Tanaka K, Sasayama T, Nishihara M , et al. Rapid regrowth of an atypical choroid plexus papilloma located in the cerebellopontine angle. J Clin Neurosci 2009; 16 (1) 121-124
    CrossrefPubMedGoogle Scholar
  • 11 Bonneville F, Savatovsky J, Chiras J. Imaging of cerebellopontine angle lesions: an update. Part 1: enhancing extra-axial lesions. Eur Radiol 2007; 17 (10) 2472-2482
    CrossrefPubMedGoogle Scholar
  • 12 Casar Borota O, Jacobsen EA, Scheie D. Bilateral atypical choroid plexus papillomas in cerebellopontine angles mimicking neurofibromatosis 2. Acta Neuropathol 2006; 111 (5) 500-502
    CrossrefPubMedGoogle Scholar
  • 13 Li S, Savolaine ER. Imaging of atypical choroid plexus papillomas. Clin Imaging 1996; 20 (2) 85-90
    CrossrefPubMedGoogle Scholar
  • 14 Martin N, Pierot L, Sterkers O, Mompoint D, Nahum H. Primary choroid plexus papilloma of the cerebellopontine angle: MR imaging. Neuroradiology 1990; 31 (6) 541-543
    CrossrefPubMedGoogle Scholar
  • 15 Tasdemiroglu E, Awh MH, Walsh JW. MRI of cerebellopontine angle choroid plexus papilloma. Neuroradiology 1996; 38 (1) 38-40
    CrossrefPubMedGoogle Scholar
  • 16 Bonneville F, Savatovsky J, Chiras J. Imaging of cerebellopontine angle lesions: an update. Part 2: intra-axial lesions, skull base lesions that may invade the CPA region, and non-enhancing extra-axial lesions. Eur Radiol 2007; 17 (11) 2908-2920
    CrossrefPubMedGoogle Scholar
  • 17 Rovit RL, Schechter MM, Chodroff P. Choroid plexus paillomas. Observations on radiographic diagnosis. Am J Roentgenol Radium Ther Nucl Med 1970; 110 (3) 608-617
    CrossrefPubMedGoogle Scholar
  • 18 Peyre M, Bah A, Kalamarides M. Multifocal choroid plexus papillomas: case report. Acta Neurochir (Wien) 2012; 154 (2) 295-299
    CrossrefPubMedGoogle Scholar
  • 19 Karim A, Fowler M, McLaren B, Cardenas R, Patwardhan R, Nanda A. Concomitant choroid plexus papillomas involving the third and fourth ventricles: a case report and review of the literature. Clin Neurol Neurosurg 2006; 108 (6) 586-589
    CrossrefPubMedGoogle Scholar
  • 20 Krishnan S, Brown PD, Scheithauer BW, Ebersold MJ, Hammack JE, Buckner JC. Choroid plexus papillomas: a single institutional experience. J Neurooncol 2004; 68 (1) 49-55
    CrossrefPubMedGoogle Scholar
  • 21 Picard C, Copty M, Lavoie G, Michaud J, Bouchard R. A primary choroid plexus papilloma of the cerebellopontine angle. Surg Neurol 1979; 12 (2) 123-127
    PubMedGoogle Scholar
  • 22 Sarkar C, Sharma MC, Gaikwad S, Sharma C, Singh VP. Choroid plexus papilloma: a clinicopathological study of 23 cases. Surg Neurol 1999; 52 (1) 37-39
    CrossrefPubMedGoogle Scholar
  • 23 Tacconi L, Delfini R, Cantore G. Choroid plexus papillomas: consideration of a surgical series of 33 cases. Acta Neurochir (Wien) 1996; 138 (7) 802-810
    CrossrefPubMedGoogle Scholar
  • 24 Jia DZ, Zhou MD, Jiang YQ, Li G. Trigeminal neuralgia caused by a choroid plexus papilloma of the cerebellopontine angle: case report and review of the literature. J Int Med Res 2010; 38 (1) 289-292
    CrossrefPubMedGoogle Scholar
  • 25 Zhang W. Choroid plexus papilloma of the cerebellopontine angle, with special reference to vertebral angiographic study. Surg Neurol 1982; 18 (5) 367-371
    CrossrefPubMedGoogle Scholar
  • 26 Doglietto F, Lauretti L, Tartaglione T, Gessi M, Fernandez E, Maira G. Diffuse craniospinal choroid plexus papilloma with involvement of both cerebellopontine angles. Neurology 2005; 65 (6) 842
    CrossrefPubMedGoogle Scholar
  • 27 Zimny A, Sasiadek M. Contribution of perfusion-weighted magnetic resonance imaging in the differentiation of meningiomas and other extra-axial tumors: case reports and literature review. J Neurooncol 2011; 103 (3) 777-783
    CrossrefPubMedGoogle Scholar
  • 28 Girardot C, Boukobza M, Lamoureux JP , et al. Choroid plexus papillomas of the posterior fossa in adults: MR imaging and gadolinium enhancement. Report of four cases and review of the literature. J Neuroradiol 1990; 17 (4) 303-318
    PubMedGoogle Scholar
  • 29 Jackson A, Panizza BJ, Hughes D, Reid H. Primary choroid plexus papilloma of the cerebellopontine angle: magnetic resonance imaging, computed tomographic and angiographic appearances. Br J Radiol 1992; 65 (777) 754-757
    CrossrefPubMedGoogle Scholar
  • 30 García-Valtuille R, Abascal F, García-Valtuille AI , et al. Adult choroid plexus papilloma of the posterior fossa mimicking a hemangioblastoma. Case report. J Neurosurg 2000; 92 (5) 870-872
    CrossrefPubMedGoogle Scholar
  • 31 Kieserman S, Linstrom C, McCormick S, Petschenik AJ. Choroid plexus papilloma of the cerebellopontine angle. Am J Otol 1996; 17 (1) 119-122
    PubMedGoogle Scholar
  • 32 Cho YD, Choi GH, Lee SP, Kim JK. (1)H-MRS metabolic patterns for distinguishing between meningiomas and other brain tumors. Magn Reson Imaging 2003; 21 (6) 663-672
    CrossrefPubMedGoogle Scholar
  • 33 Majós C, Cucurella G, Aguilera C, Coll S, Pons LC. Intraventricular meningiomas: MR imaging and MR spectroscopic findings in two cases. AJNR Am J Neuroradiol 1999; 20 (5) 882-885
    PubMedGoogle Scholar
  • 34 Krieger MD, Panigrahy A, McComb JG , et al. Differentiation of choroid plexus tumors by advanced magnetic resonance spectroscopy. Neurosurg Focus 2005; 18 (6A): E4
    PubMedGoogle Scholar
  • 35 Horská A, Ulug AM, Melhem ER , et al. Proton magnetic resonance spectroscopy of choroid plexus tumors in children. J Magn Reson Imaging 2001; 14 (1) 78-82
    CrossrefPubMedGoogle Scholar
  • 36 Shibata Y, Katayama W, Kawamura H, Anno I, Matsumura A. Proton magnetic resonance spectroscopy and 201Thallium-, 99mTechnetium methoxyisobutylisonitrile single photon emission computed tomography findings of a patient with choroid plexus papilloma. Neuroradiology 2008; 50 (8) 741-742
    CrossrefPubMedGoogle Scholar
  • 37 Krishnan S, Brown PD, Scheithauer BW, Ebersold MJ, Hammack JE, Buckner JC. Choroid plexus papillomas: a single institutional experience. J Neurooncol 2004; 68 (1) 49-55
    CrossrefPubMedGoogle Scholar